tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate

Base Information

Chemical Name:tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate
CAS No.:855481-96-8
Molecular Formula:C₂₀H₂₅BrN₂O₃
Molecular Weight:421.334
Hs Code.:

Synonyms:tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate

Suppliers and Price of tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate

There total 2 articles about tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (1R)-2-[[2-(4-bromophenyl)ethyl]amino]-1-(pyridin-3-yl)ethanol dihydrochloride

: 24424-99-5
di-tert-butyl dicarbonate

: 855481-96-8
tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 1.3h; pH=7.5 - 7.6;

Reference yield:

: 855594-20-6
C₁₅H₁₇BrN₂O

: 24424-99-5
di-tert-butyl dicarbonate

: 855481-96-8
tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 2h; pH=7 - 8;
DOI:10.1021/jm8000345

Reference yield: 63.0%

: 855481-96-8
tert-butyl [2-(4-bromophenyl)ethyl][(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]carbamate

: 855482-72-3
[3-(cyclohexyloxy)-4-(methoxycarbonyl)phenyl]boronic acid

: 881408-77-1
methyl 4'-(2-{(tert-butoxycarbonyl)[(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]amino}ethyl)-3-(cyclohexyloxy)-4-biphenylcarboxylate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; at 70 ℃; for 5h; Inert atmosphere;
DOI:10.1021/jm8000345