cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one

Base Information

Chemical Name:cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one
CAS No.:123976-16-9
Molecular Formula:C₁₉H₁₆Cl₂O₄S
Molecular Weight:411.306
Hs Code.:

Synonyms:cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one

There total 2 articles about cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 123976-14-7
(-)-(R)-(Z)-1-<3-(3,4-methylenedioxyphenyl)propenyl> p-tolyl sulphoxide

: 76-02-8
trifluoroacetyl chloride

: 123976-16-9
cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one

Guidance literature:: With zinc; In tetrahydrofuran; at -25 ℃; for 0.5h;

Reference yield:

: 61187-71-1
(+)-(R)-(dimethoxyphosphoryl)methyl p-tolyl sulfoxide

: 123976-16-9
cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / butyl-lithium / tetrahydrofuran; hexane / 0.5 h / -75 - -70 °C

2: 94 percent / zinc powder / tetrahydrofuran / 0.5 h / -25 °C

With n-butyllithium; zinc; In tetrahydrofuran; hexane;

Reference yield:

: 123976-16-9
cis-3,3-dichloro-4-(3,4-methylenedioxyphenyl)methyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one

: 17187-75-6
(+)-podorhizone

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / zinc powder, acetic acid / 0.5 h / Ambient temperature

2: 91 percent / tributyltin hydride, azoisobutyronitrile / toluene / 0.5 h / 90 °C

3: 90 percent / lithium di-isopropylamide / tetrahydrofuran; hexane / 0.25 h / -70 °C

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; acetic acid; zinc; lithium diisopropyl amide; In tetrahydrofuran; hexane; toluene;