BW A522

Base Information

• Chemical Name: BW A522
• CAS No.: 112533-64-9
• Molecular Formula: C₂₃H₂₂IN₅O₅
• Molecular Weight: 575.363
• Mol file: 112533-64-9.mol

Synonyms:Aceticacid, [4-[3-[(4-amino-3-iodophenyl)methyl]-2,3,6,7-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl]phenoxy]-(9CI); BW-A 522

Chemical Property of BW A522

Chemical Property:

• Vapor Pressure: 2.68E-27mmHg at 25°C
• Boiling Point: 804.1°C at 760 mmHg
• Flash Point: 440.1°C
• PSA: 145.23000
• Density: 1.691g/cm³
• LogP: 3.24300

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BW A522

There total 1 articles about BW A522 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{4-[3-(4-Amino-benzyl)-2,6-dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl]-phenoxy}-acetic acid ethyl ester (112533-60-5) → 3-(4-amino-3-iodobenzyl)-8-[4-[[[carboxy]methyl]oxy]phenyl]-1-propylxanthine (112533-64-9)

Guidance literature:

With sodium hydroxide; iodine; sodium hydrogencarbonate; Yield given. Multistep reaction; 1.) reflux, 2.) RT;

DOI:10.1021/jm00399a010

Reference yield: 15.0%

3-(4-amino-3-iodobenzyl)-8-[4-[[[carboxy]methyl]oxy]phenyl]-1-propylxanthine (112533-64-9) → {4-[3-(4-Azido-3-iodo-benzyl)-2,6-dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl]-phenoxy}-acetic acid (112533-68-3)

Guidance literature:

With sodium azide; acetic acid; sodium nitrite;

DOI:10.1021/jm00399a010

upstream raw materials:

{4-[3-(4-Amino-benzyl)-2,6-dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl]-phenoxy}-acetic acid ethyl ester

Downstream raw materials:

{4-[3-(4-Azido-3-iodo-benzyl)-2,6-dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl]-phenoxy}-acetic acid

Refernces