125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors.

DOI: 10.1021/jm00399a010

Source and publish data:

Journal of medicinal chemistry p. 745 - 751 (1988)

Update date:2022-08-05

Topics:

Authors:

Linden Linden

Patel Patel

Earl Earl

Craig Craig

Daluge Daluge

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Article abstract of DOI:10.1021/jm00399a010

A series of 8-phenylxanthine derivatives has been synthesized with oxyacetic acid on the para phenyl position to increase aqueous solubility and minimize nonspecific binding and iodinatable groups on the 1- or 3-position of the xanthine ring. The structur

Full text of DOI:10.1021/jm00399a010

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