4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile

Base Information

• Chemical Name: 4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile
• CAS No.: 1071933-07-7
• Molecular Formula: C₁₀H₇F₇N₂O
• Molecular Weight: 304.167
• Mol file: 1071933-07-7.mol

Synonyms:4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile

Chemical Property of 4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile

There total 1 articles about 4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethene (74-85-1) + (nickel(II))(PPh3)(C6H2Me3)(4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile(-1H)) → 1-butylene (106-98-9,9003-28-5) + 1-hexene (592-41-6,25067-06-5) + oct-1-ene (111-66-0,25068-25-1) + 4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile (1071933-07-7) + 1-butenyl-2,4,6-trimethylbenzene (40244-38-0,40244-53-9) + 1,3,5-trimethyl-benzene (108-67-8)

Guidance literature:

In toluene; under 52505.3 Torr; Inert atmosphere; Schlenk technique; Autoclave;

DOI:10.1016/j.jorganchem.2012.08.030

Reference yield: 88.0%

trans-(bromomesityl)bis(triphenylphosphino)nickel(II) + 4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile (1071933-07-7) → (nickel(II))(PPh3)(C6H2Me3)(4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile(-1H))

Guidance literature:

With NaN(Si(CH₃)3)2; In toluene; under N2, standard Schlenk techniques; nitrile dissolved in toluene, soln. of amide in toluene added, mixt. stirred for 2 h, soln. of Ni complexin toluene added dropwise under stirring, mixt. stirred overnight; mixt. filtered through Celite, filtrate evapd. under vac., pentane added, stirred overnight, ppt. filtered off, washed with pentane, dried undervac.; elem. anal.;

DOI:10.1002/ejic.200901196

Reference yield: 81.0%

trans-(o-tolyl)bromobis(triphenylphosphine)nickel(II) + 4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[pyrrolidin-(2Z)-ylidene]hexanenitrile (1071933-07-7) → (Rp)/(Sp)-(SP-4-3)-[Ni(4,4,5,5,6,6,6-heptafluoro-3-oxo-2-pyrrolidin-(2Z)-ylidenehexanenitrile)(2-toluenido)(PPh3)]

Guidance literature:

With NaN(Si(CH₃)3)2; In toluene; under N2, standard Schlenk techniques; nitrile dissolved in toluene, soln. of amide in toluene added, mixt. stirred for 2 h, soln. of Ni complexin toluene added dropwise under stirring, mixt. stirred overnight; mixt. filtered through Celite, filtrate evapd. under vac., pentane added, stirred overnight, ppt. filtered off, washed with pentane, dried undervac.; elem. anal.;

DOI:10.1002/ejic.200901196

upstream raw materials:

ethene