1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene

Base Information

Chemical Name:1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene
CAS No.:42908-82-7
Molecular Formula:C₈H₄F₆O
Molecular Weight:230.11
Hs Code.:
DSSTox Substance ID:DTXSID301242430
Nikkaji Number:J3.539.271H

Synonyms:1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene;42908-82-7;SCHEMBL11527555;ACUIYXQIANMNHW-UHFFFAOYSA-N;DTXSID301242430;AKOS016016227;A903041

Suppliers and Price of 1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:230.01663372
Heavy Atom Count:15
Complexity:208

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC(F)(F)F)C(F)(F)F

Technology Process of 1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene

There total 4 articles about 1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: α,α-difluoro(3-trifluoromethylphenoxy)acetic acid

: 42908-82-7
m-(trifluoromethoxy)-α,α,α-trifluorotoluene

Guidance literature:: With trifluorormethanesulfonic acid; selectfluor II; silver nitrate; In dichloromethane; water; at 80 ℃; for 24h; Inert atmosphere;
DOI:10.1021/acs.orglett.6b01779

Reference yield:

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 98-08-8
α,α,α-trifluorotoluene

: 401-80-9
3-fluoro-trifluoromethylbenzene

: 42908-82-7
m-(trifluoromethoxy)-α,α,α-trifluorotoluene

Guidance literature:: In 1,2-dichlorotrifluoroethyl-trifluoromethylether; at -40 ℃; Inert atmosphere;
DOI:10.1016/j.jfluchem.2012.04.008

Reference yield:

: 1006904-72-8
silver(I) trifluoromethoxide

: 98-16-8
3-trifluoromethylaniline

: 42908-82-7
m-(trifluoromethoxy)-α,α,α-trifluorotoluene

Guidance literature:: 3-trifluoromethylaniline; With tetrafluoroboric acid; tert.-butylnitrite; In ethanol; at 0 - 20 ℃; for 1h; Schlenk technique;

silver(I) trifluoromethoxide; In acetonitrile; at -40 - 20 ℃;
DOI:10.1021/acs.orglett.9b03000