2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester

Base Information

• Chemical Name: 2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester
• CAS No.: 169687-12-1
• Molecular Formula: C₁₉H₂₂O₆S
• Molecular Weight: 378.446
• Mol file: 169687-12-1.mol

Synonyms:2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester

Chemical Property of 2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester

There total 1 articles about 2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl (2-methyl-2-propenyl)-propanedioate (50598-40-8) + 2,3-bis(phenylsulfonyl)-1,3-butadiene (85540-20-1) → 2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester (169687-12-1)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) THF, 0 deg C, 20 min, 2.) THF, 5 min;

DOI:10.1021/ja00132a005

Reference yield: 98.0%

2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester (169687-12-1) → 5-(phenylsulfonyl)-1-methyl-6-methylenebicyclo<3.2.0>heptane-3,3-dicarboxylic acid dimethyl ester

Guidance literature:

In xylene; for 6h; Heating;

DOI:10.1021/ja00132a005

Reference yield: 88.0%

carbon monoxide (201230-82-2) + 2-<2-(phenylsulfonyl)buta-2,3-dienyl>-2-(2-methylallyl)malonic acid dimethyl ester (169687-12-1) → (+/-)-(2S,6S)-4,4-bis(methoxycarbonyl)-6-methyl-2-(phenylsulfonyl)bicyclo[4.3.0]non-1(9)-en-8-one

Guidance literature:

With [{RhCl(CO)dppp}2]; In toluene; for 1h; under 760.051 Torr; Inert atmosphere; Reflux;

DOI:10.3762/bjoc.7.52

upstream raw materials:

dimethyl (2-methyl-2-propenyl)-propanedioate

2,3-bis(phenylsulfonyl)-1,3-butadiene