N-phenyl thiophene carboxamidine-3

Base Information

• Chemical Name: N-phenyl thiophene carboxamidine-3
• CAS No.: 59918-76-2
• Molecular Formula: C₁₁H₁₀N₂S
• Molecular Weight: 202.28
• Mol file: 59918-76-2.mol

Synonyms:N-phenyl thiophene carboxamidine-3

Chemical Property of N-phenyl thiophene carboxamidine-3

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N-phenyl thiophene carboxamidine-3

There total 2 articles about N-phenyl thiophene carboxamidine-3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-thiophenecarbonitrile (1641-09-4) + aniline (62-53-3) → N-phenyl thiophene carboxamidine-3 (59918-76-2)

Guidance literature:

With sodium hydride; In dimethyl sulfoxide; mineral oil; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/d1gc01493e

Reference yield:

→ N-phenyl thiophene carboxamidine-3 (59918-76-2)

Guidance literature:

/BRN= 796056/, OH-;

Reference yield: 78.0%

4-methoxyphenylacetylen (768-60-5) + N-phenyl thiophene carboxamidine-3 (59918-76-2) → (4-methoxyphenyl) (2-(thiophen-3-yl) quinazolin-4-yl) methanone

Guidance literature:

With oxygen; potassium carbonate; copper(l) chloride; In methanol; dichloromethane; at 25 - 28 ℃; for 22h; Irradiation; Green chemistry;

DOI:10.1039/d1gc01493e

upstream raw materials:

3-thiophenecarbonitrile

aniline

Refernces