1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol

Base Information

• Chemical Name: 1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol
• CAS No.: 634922-73-9
• Molecular Formula: C₂₂H₃₀O₈
• Molecular Weight: 422.475
• Mol file: 634922-73-9.mol

Synonyms:1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol

Chemical Property of 1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol

There total 5 articles about 1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,4',4-trimethoxymethoxy-3'-methoxychalcone (634922-72-8) → 1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol (634922-73-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; under 1520 Torr;

DOI:10.1081/SCC-120024733

Reference yield:

3-methoxy-4-methoxymethoxy-benzaldehyde (5533-00-6) → 1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol (634922-73-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 70 percent / diethyl ether / 0.5 h / Heating

2: 85 percent / PCC / CH₂Cl₂ / 1.5 h / 20 °C

3: 85 percent / KOH / methanol / 20 °C

4: 99 percent / H₂ / Pd-C / ethanol / 20 °C / 1520 Torr

With potassium hydroxide; hydrogen; pyridinium chlorochromate; palladium on activated charcoal; In methanol; diethyl ether; ethanol; dichloromethane;

DOI:10.1081/SCC-120024733

Reference yield:

1-<3-methoxy-4-(methoxymethoxy)phenyl>ethanone (143418-77-3) → 1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol (634922-73-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / KOH / methanol / 20 °C

2: 99 percent / H₂ / Pd-C / ethanol / 20 °C / 1520 Torr

With potassium hydroxide; hydrogen; palladium on activated charcoal; In methanol; ethanol;

DOI:10.1081/SCC-120024733

upstream raw materials:

2,4',4-trimethoxymethoxy-3'-methoxychalcone

3-methoxy-4-methoxymethoxy-benzaldehyde

1-<3-methoxy-4-(methoxymethoxy)phenyl>ethanone

vanillin

Downstream raw materials:

(+/-)-7,4'-dimethoxymethoxy-3'-methoxyflavan

(+/-)-7,4'-Dihydroxy-3'-methoxyflavan