dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate

Base Information

• Chemical Name: dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate
• CAS No.: 1006866-45-0
• Molecular Formula: C₂₉H₂₄O₅
• Molecular Weight: 452.507
• Mol file: 1006866-45-0.mol

Synonyms:dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate

Chemical Property of dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate

There total 5 articles about dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-(1-pyrenyl)-3-bromopropane (61098-95-1) + Dimethyl 5-hydroxyisophthalate (13036-02-7) → dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate (1006866-45-0)

Guidance literature:

With potassium carbonate; potassium iodide; In acetonitrile; for 8h; Heating;

DOI:10.1021/ja0759139

Reference yield:

3-(pyrene-1-yl)propan-1-ol (61098-94-0) + Dimethyl 5-hydroxyisophthalate (13036-02-7) → dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate (1006866-45-0)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at -78 ℃; for 3.08333h; Reflux;

DOI:10.1021/ol303403x

Reference yield:

3-(1-pyrenyl)propionic acid (61098-93-9) → dimethyl 5-(3-(pyren-1-yl)propoxy)isophthalate (1006866-45-0)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C / Cooling

2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 3.08 h / -78 °C / Reflux

With lithium aluminium tetrahydride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 2: |Mitsunobu Displacement;

DOI:10.1021/ol303403x

upstream raw materials:

1-(1-pyrenyl)-3-bromopropane

Dimethyl 5-hydroxyisophthalate

3-(1-pyrenyl)propionic acid

3-(pyrene-1-yl)propan-1-ol

Downstream raw materials:

{5-[3-(pyren-1-yl)propoxy]-1,3-phenylene}dimethanol

5-(3-(pyren-1-yl)propoxy)-α,α’-dibromo-m-xylene

5-(3-(pyren-1-yl)propoxy)-α,α’-bis((di-2-picolyl)amino)-m-xylene

Refernces

• 1、 Oh, Jinrok,Hong, Jong-In. "Discrimination of redox-responsible biomolecules by a single molecular sensor". . p. 1210 - 1213. Retrieved 2013/05/09.