(2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

Base Information

Chemical Name:(2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)
CAS No.:1186527-15-0
Molecular Formula:C₄₉H₄₁N₃O₁₉S₃Si
Molecular Weight:1100.16
Hs Code.:

(2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

Synonyms:(2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

Suppliers and Price of (2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

There total 3 articles about (2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1186527-14-9
(2R,3R)-2-(3,4-dihydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

: 58479-61-1
tert-butylchlorodiphenylsilane

: 1186527-15-0
(2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

Guidance literature:: With triethylamine; In acetonitrile; at -20 ℃; for 3h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.bmcl.2009.05.111

Reference yield:

: 970-73-0,1617-55-6,3371-27-5,13425-13-3,136892-45-0,970-74-1,98032-84-9
epigallocatechin

: 1186527-15-0
(2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; boric acid / water; toluene / 3.5 h / 20 °C / pH 9 / Inert atmosphere

2: triethylamine / acetonitrile / 3 h / -20 °C / Inert atmosphere

With boric acid; triethylamine; sodium hydroxide; In water; toluene; acetonitrile;
DOI:10.1038/ja.2016.14

Reference yield:

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 1186527-15-0
(2R,3R)-2-(3-tert-butyldiphenylsilyloxy-4-hydroxy-5-(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate)

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; boric acid / water; toluene / 3.5 h / 20 °C / pH 9 / Inert atmosphere

2: triethylamine / acetonitrile / 3 h / -20 °C / Inert atmosphere

With boric acid; triethylamine; sodium hydroxide; In water; toluene; acetonitrile;
DOI:10.1038/ja.2016.14