Technology Process of 4,4'-diiodo-(N',N'''-dibenzoyl)diphenic acid dihydrazide
There total 6 articles about 4,4'-diiodo-(N',N'''-dibenzoyl)diphenic acid dihydrazide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 67 percent / ammonium formate / Pd/C / dimethylformamide / 5 h / 80 °C
2.1: HCl; NaNO2 / acetonitrile; H2O / 0.5 h / 0 °C
2.2: 93 percent / KI / acetonitrile; H2O
3.1: 84 percent / hydrazine / ethanol; toluene / 24 h / 110 °C
4.1: 96 percent / 1-methyl-pyrrolidin-2-one / 0 °C
With
hydrogenchloride; ammonium formate; hydrazine; sodium nitrite;
palladium on activated charcoal;
In
1-methyl-pyrrolidin-2-one; ethanol; water; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1021/ol062668+
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: HNO3; H2SO4 / H2O / 1 h / 0 °C
2.1: 50.0 g / H2SO4 / 24 h / 80 °C
3.1: 67 percent / ammonium formate / Pd/C / dimethylformamide / 5 h / 80 °C
4.1: HCl; NaNO2 / acetonitrile; H2O / 0.5 h / 0 °C
4.2: 93 percent / KI / acetonitrile; H2O
5.1: 84 percent / hydrazine / ethanol; toluene / 24 h / 110 °C
6.1: 96 percent / 1-methyl-pyrrolidin-2-one / 0 °C
With
hydrogenchloride; sulfuric acid; nitric acid; ammonium formate; hydrazine; sodium nitrite;
palladium on activated charcoal;
In
1-methyl-pyrrolidin-2-one; ethanol; water; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1021/ol062668+
