2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside

Base Information

• Chemical Name: 2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside
• CAS No.: 113764-99-1
• Molecular Formula: C₅₂H₅₅Cl₃O₁₁
• Molecular Weight: 962.361
• Mol file: 113764-99-1.mol

Synonyms:2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside

Chemical Property of 2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside

There total 8 articles about 2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl bromide (4196-35-4) + 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside (113764-92-4) → 2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside (113764-99-1)

Guidance literature:

With 4 A molecular sieve; tetraethylammonium bromide; In dichloromethane; for 168h; Ambient temperature;

DOI:10.1016/0008-6215(87)80151-9

Reference yield: 35.0%

tetra-O-benzyl glucopyranosyl chloride (25320-59-6) + 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside (113764-92-4) → 2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside (113764-99-1)

Guidance literature:

With mercury(II) cyanide; In nitromethane; benzene; at 45 ℃; for 96h;

DOI:10.1016/0008-6215(87)80151-9

Reference yield: 26.0%

tetra-O-benzyl glucopyranosyl chloride (25320-59-6) + 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside (113764-92-4) → 2,3,4,6-tetra-O-benzyl 1,5-anhydro-D-arabino-hex-1-enitol (4132-26-7) + 2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside (113764-99-1)

Guidance literature:

With potassium hydroxide; 18-crown-6 ether; In isopropyl alcohol; benzene; for 48h; Product distribution; other reagent, temperature and reaction time;

DOI:10.1016/0008-6215(87)80151-9

upstream raw materials:

2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl bromide

2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside

tetra-O-benzyl glucopyranosyl chloride

benzaldehyde

Downstream raw materials:

2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α/β-D-glucopyranoside