2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside

Base Information

• Chemical Name: 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside
• CAS No.: 113764-92-4
• Molecular Formula: C₁₈H₂₁Cl₃O₆
• Molecular Weight: 439.72
• Mol file: 113764-92-4.mol

Synonyms:2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside

Chemical Property of 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside

There total 5 articles about 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,2,2-trichloroethyl 4,6-O-benzylidene-β-D-glucopyranoside (109363-12-4) + allyl bromide (106-95-6) → 2,2,2-trichloroethyl-3-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside (113764-93-5) + 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside (113764-92-4)

Guidance literature:

With sodium hydroxide; tetrabutylammomium bromide; In dichloromethane; for 8h; Ambient temperature;

DOI:10.1016/0008-6215(87)80151-9

Reference yield:

benzaldehyde (100-52-7) → 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside (113764-92-4)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc chloride / 72 h

2: 72 percent / tetra-n-butylammonium bromide, 10percent aq. sodium hydroxide / CH₂Cl₂ / 8 h / Ambient temperature

With sodium hydroxide; tetrabutylammomium bromide; zinc(II) chloride; In dichloromethane;

DOI:10.1016/0008-6215(87)80151-9

Reference yield:

2,2,2-trichloroethyl D-glucopyranoside (16854-29-8,77453-95-3,81414-89-3,81555-82-0) → 2,2,2-trichloroethyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside (113764-92-4)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc chloride / 72 h

2: 72 percent / tetra-n-butylammonium bromide, 10percent aq. sodium hydroxide / CH₂Cl₂ / 8 h / Ambient temperature

With sodium hydroxide; tetrabutylammomium bromide; zinc(II) chloride; In dichloromethane;

DOI:10.1016/0008-6215(87)80151-9

upstream raw materials:

2,2,2-trichloroethyl 4,6-O-benzylidene-β-D-glucopyranoside

allyl bromide

benzaldehyde

2,2,2-trichloroethyl D-glucopyranoside

Downstream raw materials:

2,3,4,6-tetra-O-benzyl 1,5-anhydro-D-arabino-hex-1-enitol

2,2,2-trichloroethyl 2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranoside

2-O-allyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α/β-D-glucopyranoside

2,2,2-trichloroethyl 3-O-acetyl-2-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside