ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate

Base Information

Chemical Name:ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate
CAS No.:1414973-37-7
Molecular Formula:C₁₉H₂₀ClN₃O
Molecular Weight:341.84
Hs Code.:

Synonyms:ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate

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Technology Process of ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate

There total 3 articles about ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1414973-13-9
2-amino-4-(4-chlorophenyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile

: 122-51-0
orthoformic acid triethyl ester

: 1414973-37-7
ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate

Guidance literature:: Reflux;
DOI:10.1007/s00044-012-0272-y

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 1414973-37-7
ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / ethanol / 6 h / Reflux

2: Reflux

With ammonium acetate; In ethanol;
DOI:10.1007/s00044-012-0272-y

Reference yield:

: 1867-38-5
4-chlorobenzylidenemalonodinitrile

: 1414973-37-7
ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / ethanol / 6 h / Reflux

2: Reflux

With ammonium acetate; In ethanol;
DOI:10.1007/s00044-012-0272-y