C₂₈H₃₁NO₄

Base Information

• Chemical Name: C₂₈H₃₁NO₄
• CAS No.: 1332981-46-0
• Molecular Formula: C₂₈H₃₁NO₄
• Molecular Weight: 445.558
• Mol file: 1332981-46-0.mol

Synonyms:C₂₈H₃₁NO₄

Chemical Property of C₂₈H₃₁NO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₃₁NO₄

There total 3 articles about C₂₈H₃₁NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

C28H31NO5 (1332981-48-2) → C28H31NO4 (1332981-46-0)

Guidance literature:

With 20% palladium hydroxide on charcoal; hydrogen; In tetrahydrofuran; acetic acid; at 20 ℃; for 18h; under 760.051 Torr;

DOI:10.1016/j.bmcl.2011.06.110

Reference yield:

3-carboxamidobenzaldehyde (126534-87-0) → C28H31NO4 (1332981-46-0)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hexamethyldisilazane / tetrahydrofuran / 2 h / -78 °C

2: hydrogenchloride; water / methanol / 3.5 h / 20 °C

3: 20% palladium hydroxide on charcoal; hydrogen / tetrahydrofuran; acetic acid / 18 h / 20 °C / 760.05 Torr

With hydrogenchloride; 20% palladium hydroxide on charcoal; water; hydrogen; sodium hexamethyldisilazane; In tetrahydrofuran; methanol; acetic acid;

DOI:10.1016/j.bmcl.2011.06.110

Reference yield:

3'-(tert-butyldimethylsilyloxy)-1,3,5(10)-estratrien-17β-O,16β-ethanolactone → C28H31NO4 (1332981-46-0)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hexamethyldisilazane / tetrahydrofuran / 2 h / -78 °C

2: hydrogenchloride; water / methanol / 3.5 h / 20 °C

3: 20% palladium hydroxide on charcoal; hydrogen / tetrahydrofuran; acetic acid / 18 h / 20 °C / 760.05 Torr

With hydrogenchloride; 20% palladium hydroxide on charcoal; water; hydrogen; sodium hexamethyldisilazane; In tetrahydrofuran; methanol; acetic acid;

DOI:10.1016/j.bmcl.2011.06.110

upstream raw materials:

C₂₈H₃₁NO₅

3-carboxamidobenzaldehyde