3-fluoro-3-phenylazetidine hydrochloride

Base Information

Chemical Name:3-fluoro-3-phenylazetidine hydrochloride
CAS No.:1126650-56-3
Molecular Formula:C₉H₁₀FN*ClH
Molecular Weight:187.644
Hs Code.:

Synonyms:3-fluoro-3-phenylazetidine hydrochloride

Suppliers and Price of 3-fluoro-3-phenylazetidine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Fluoro-3-phenylazetidineHydrochloride
2.5mg
$ 65.00

Crysdot
3-Fluoro-3-phenylazetidinehydrochloride 97%
250mg
$ 782.00

Chemenu
3-Fluoro-3-phenylazetidinehydrochloride 95+%
250mg
$ 739.00

AK Scientific
3-Fluoro-3-phenylazetidinehydrochloride
500mg
$ 1437.00

Total 1 raw suppliers

Chemical Property of 3-fluoro-3-phenylazetidine hydrochloride

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

3-Fluoro-3-phenylazetidineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-fluoro-3-phenylazetidine hydrochloride

There total 3 articles about 3-fluoro-3-phenylazetidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1126650-55-2
tert-butyl 3-fluoro-3-phenylazetidine-1-carboxylate

: 1126650-56-3
3-fluoro-3-phenylazetidine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; at 20 ℃; for 1h;
DOI:10.1021/jo802791r

Reference yield:

: 100-58-3
phenylmagnesium bromide

: 1126650-56-3
3-fluoro-3-phenylazetidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; diethyl ether / 2 h / 0 - 20 °C

2: (bis-(2-methoxyethyl)amino)sulfur trufluoride / dichloromethane; toluene / 20 h / -78 - 20 °C

3: hydrogenchloride / isopropyl alcohol; diethyl ether / 18 h / 0 - 20 °C

With hydrogenchloride; (bis-(2-methoxyethyl)amino)sulfur trufluoride; In tetrahydrofuran; diethyl ether; dichloromethane; isopropyl alcohol; toluene;
DOI:10.1021/jacs.0c05131

Reference yield:

: 398489-25-3
tert-butyl 3-hydroxy-3-phenylazetidine-1-carboxylate

: 1126650-56-3
3-fluoro-3-phenylazetidine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: (bis-(2-methoxyethyl)amino)sulfur trufluoride / dichloromethane; toluene / 20 h / -78 - 20 °C

2: hydrogenchloride / isopropyl alcohol; diethyl ether / 18 h / 0 - 20 °C

With hydrogenchloride; (bis-(2-methoxyethyl)amino)sulfur trufluoride; In diethyl ether; dichloromethane; isopropyl alcohol; toluene;
DOI:10.1021/jacs.0c05131