3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one

Base Information

• Chemical Name: 3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one
• CAS No.: 1610693-06-5
• Molecular Formula: C₁₃H₁₃ClO₅S
• Molecular Weight: 316.762
• Mol file: 1610693-06-5.mol

Synonyms:3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one

Chemical Property of 3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one

There total 4 articles about 3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

3-chloro-5-ethoxy-4-(4-methylphenylsulfanyl)furan-2(5H)-one (1610693-00-9) → 3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one (1610693-06-5)

Guidance literature:

With dihydrogen peroxide; In water; acetic acid; at 20 ℃; for 96h;

DOI:10.1134/S1070428014040149

Reference yield:

3,4-dichloro-5-ethoxy-2,5-dihydrofuran-2-one (40882-43-7) + sodium 4-methylbenzenesulfinate (824-79-3) → 3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one (1610693-06-5)

Guidance literature:

With tetrabutylammomium bromide; In water; 1,2-dichloro-ethane; at 90 ℃; for 8h;

DOI:10.1039/c9ob00736a

Reference yield:

3-chloro-5-hydroxy-4-[(4-methylphenylsulfanyl)]-2(5H)-furanone → 3-chloro-5-ethoxy-4-(4-methylphenylsulfonyl)furan-2(5H)-one (1610693-06-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / benzene / 70 h / Reflux

2: dihydrogen peroxide / acetic acid; water / 96 h / 20 °C

With sulfuric acid; dihydrogen peroxide; In water; acetic acid; benzene;

DOI:10.1134/S1070428014040149

upstream raw materials:

3-chloro-5-ethoxy-4-(4-methylphenylsulfanyl)furan-2(5H)-one

para-thiocresol

3,4-dichloro-5-ethoxy-2,5-dihydrofuran-2-one

sodium 4-methylbenzenesulfinate