C₁₇H₁₈N₂O₅

Base Information

• Chemical Name: C₁₇H₁₈N₂O₅
• CAS No.: 1068432-29-0
• Molecular Formula: C₁₇H₁₈N₂O₅
• Molecular Weight: 330.34
• Mol file: 1068432-29-0.mol

Synonyms:C₁₇H₁₈N₂O₅

Chemical Property of C₁₇H₁₈N₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₈N₂O₅

There total 6 articles about C₁₇H₁₈N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 2-methoxy-3-(2-methoxy-3-nitrobenzamido)benzoate (1068432-28-9) → C17H18N2O5 (1068432-29-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 40 ℃; for 3h;

DOI:10.1021/ol801980h

Reference yield: 24.0%

2-methoxy-3-methoxycarbonylaniline (5129-25-9) → C17H18N2O5 (1068432-29-0) + C25H25N3O7 (1068432-31-4) + C33H32N4O9 (1068432-33-6) + C41H39N5O11 (1068432-35-8) + C48H42N6O12 (1291056-36-4)

Guidance literature:

With trimethylaluminum; In tetrahydrofuran; at 70 ℃; for 12h; Reagent/catalyst; Solvent; Inert atmosphere; Sealed tube;

DOI:10.1039/c3cc48576e

Reference yield:

2-methoxy-3-nitro-benzoic acid methyl ester (90564-26-4) → C17H18N2O5 (1068432-29-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: iron; acetic acid / ethanol / 2 h / Reflux

2.1: 4-methyl-morpholine; chloroformic acid ethyl ester / dichloromethane / 0.25 h / 0 °C

2.2: 6 h / 20 °C

3.1: iron; acetic acid / ethanol / 2 h / Reflux

With 4-methyl-morpholine; chloroformic acid ethyl ester; iron; acetic acid; In ethanol; dichloromethane;

DOI:10.1039/c3cc42349b

upstream raw materials:

methyl 2-methoxy-3-(2-methoxy-3-nitrobenzamido)benzoate

2-methoxy-3-methoxycarbonylaniline

2-methoxy-3-nitro-benzoic acid methyl ester

2-hydroxy-3-nitro-benzoic acid methyl ester

Downstream raw materials:

methyl 2-methoxy-3-(2-methoxy-3-(2-methoxy-3-nitrobenzamido)benzamido)benzoate

methyl 3-(3-(2-(allyloxy)-3-nitrobenzamido)-2-methoxybenzamido)-2-methoxybenzoate

methyl 3-(3-(2-(allyloxy)-3-(2-methoxy-3-nitrobenzamido)benzamido)-2-methoxybenzamido)-2-methoxybenzoate

methyl 3-(3-(2-(allyloxy)-3-(2-methoxy-3-(2-methoxy-3-nitrobenzamido)benzamido)benzamido)-2-methoxybenzamido)-2-methoxybenzoate