N,N'-Diphenylacetamidine

Base Information

• Chemical Name: N,N'-Diphenylacetamidine
• CAS No.: 621-09-0
• Molecular Formula: C₁₄H₁₄N₂
• Molecular Weight: 210.279
• European Community (EC) Number: 210-669-2
• NSC Number: 6792
• UNII: EQX93UUJ9T
• DSSTox Substance ID: DTXSID5060728
• Nikkaji Number: J79.106G
• ChEMBL ID: CHEMBL1867908
• Mol file: 621-09-0.mol

Synonyms:N,N'-DIPHENYLACETAMIDINE;(1E)-N,N'-Diphenylethanimidamide;1452517-10-0;Ethanimidamide, N,N'-diphenyl-;621-09-0;N,N'-diphenylethanimidamide;Acetamidine, N,N'-diphenyl-;(E)-N,N'-Diphenylacetimidamide;NSC 6792;EINECS 210-669-2;EQX93UUJ9T;BRN 2804188;NSC-6792;N,N'-DI(PHENYL)ETHANIMIDAMIDE;(E)-N,N'-DIPHENYLETHANIMIDAMIDE;4-12-00-00384 (Beilstein Handbook Reference);NSC6792;UNII-EQX93UUJ9T;Acetamidine,N'-diphenyl-;N,N'-Diphenyl-acetamidine;N,N'-diphenylacetimidamide;Cambridge id 5135256;Ethanimidamide,N'-diphenyl-;MLS000105031;SCHEMBL167176;CHEMBL1867908;DTXSID5060728;HMS1577H21;HMS2339F22;N^1^, N^2^-Diphenylacetamidine;MFCD00137802;AKOS003672330;LS-04297;SMR000054960;CS-0368037;A909406;SR-01000196545;SR-01000196545-1

Chemical Property of N,N'-Diphenylacetamidine

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 210.115698455
• Heavy Atom Count: 16
• Complexity: 223

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NC1=CC=CC=C1)NC2=CC=CC=C2

Technology Process of N,N'-Diphenylacetamidine

There total 53 articles about N,N'-Diphenylacetamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

aniline (62-53-3) + Acetanilid (103-84-4) → N,N'-diphenylacetamidine (621-09-0,141417-91-6,1086215-03-3,1452517-10-0)

Guidance literature:

Acetanilid; With magnesia; In neat (no solvent); at 70 ℃; for 0.5h;

aniline; In neat (no solvent); at 70 ℃; for 5h;

DOI:10.1016/j.tetlet.2013.05.096

Reference yield: 86.0%

acetophenone O-acetyloxime (19433-17-1) + aniline (62-53-3) → N,N'-diphenylacetamidine (621-09-0,141417-91-6,1086215-03-3,1452517-10-0)

Guidance literature:

With zinc trifluoromethanesulfonate; In acetonitrile; at 80 ℃; for 8h; Reagent/catalyst; Temperature;

DOI:10.1002/adsc.201701490

Reference yield: 75.0%

aniline (62-53-3) + acetylene (74-86-2,25067-58-7) → N,N'-diphenylacetamidine (621-09-0,141417-91-6,1086215-03-3,1452517-10-0) + Acetanilid (103-84-4)

Guidance literature:

With mercury(II) diacetate; In tetrahydrofuran; for 4h; Ambient temperature;

upstream raw materials:

phosgene

N-phenylglycine anilide

thioacetanilide

acetic acid

Downstream raw materials:

N-phenylphthalimide

Acetanilid

2-Methyl-3-phenyl-4(3H)-quinazolinone

aniline