Technology Process of methyl 4-benzyloxy-3,6-dihydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate
There total 10 articles about methyl 4-benzyloxy-3,6-dihydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
toluene;
for 1h;
Heating;
dark;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 71 percent / NaOMe / methanol / 4 °C
2: xylene / Heating
3: LiAlH4 / diethyl ether / Heating
4: 84 percent / MnO2 / CH2Cl2 / Heating
5: 70 percent / (Ph3P)2Rh(CO)Cl, 1,3-bis(diphenylphosphino)propane / 1,3,5-trimethyl-benzene / Heating
6: 57 percent / 1.) t-BuLi / 1.) THF, -78 deg C, 2.) -78 deg C to room temp.
7: NaOMe / methanol / 4 °C
8: toluene / Heating
With
manganese(IV) oxide; lithium aluminium tetrahydride; chlorocarbonylbis(triphenylphosphine)rhodium(I); 1,3-bis-(diphenylphosphino)propane; tert.-butyl lithium; sodium methylate;
In
methanol; diethyl ether; dichloromethane; toluene; xylene; 1,3,5-trimethyl-benzene;
DOI:10.1039/c39850001775
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 70 percent / (Ph3P)2Rh(CO)Cl, 1,3-bis(diphenylphosphino)propane / 1,3,5-trimethyl-benzene / Heating
2: 57 percent / 1.) t-BuLi / 1.) THF, -78 deg C, 2.) -78 deg C to room temp.
3: NaOMe / methanol / 4 °C
4: toluene / Heating
With
chlorocarbonylbis(triphenylphosphine)rhodium(I); 1,3-bis-(diphenylphosphino)propane; tert.-butyl lithium; sodium methylate;
In
methanol; toluene; 1,3,5-trimethyl-benzene;
DOI:10.1039/c39850001775
