6451-86-1

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-4-methoxy-5-(benzyloxy)benzaldehyde is used as an intermediate in the synthesis of 3,8-Dihydroxy-9-methoxy-6H-Dibenzo[b,d]pyran-6-one (D455545), a compound with potential applications in anti-wrinkle agents. It is known to promote collagen production, inhibit MMP-1 production, and reduce elastase activity, making it a valuable component in the development of anti-aging treatments.
Used in Cosmetic Industry:
In the cosmetic industry, 2-Bromo-4-methoxy-5-(benzyloxy)benzaldehyde is used as a key component in the formulation of anti-aging products. Its role in promoting collagen production and inhibiting enzymes that degrade skin elasticity contributes to the development of effective anti-wrinkle agents, helping to maintain youthful and healthy skin appearance.

InChI:InChI=1/C15H13BrO3/c1-18-14-8-13(16)12(9-17)7-15(14)19-10-11-5-3-2-4-6-11/h2-9H,10H2,1H3

Upstream product

• 2973-59-3 2-bromoisovanillin 
• 100-44-7 benzyl chloride 
• 6346-05-0 3-benzyloxy-4-methoxybenzaldehyde 
• 100-39-0 benzyl bromide 
• 881-57-2 isovanillin acetate 
• 69048-79-9 4-bromo-5-formyl-2-methoxyphenyl acetate 
• 13397-01-8 [5-(benzyloxy)-2-bromo-4-methoxyphenyl]methanol 
• 120-57-0 piperonal 
• 100-51-6 benzyl alcohol 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 621-59-0 isovanillin 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 40705-20-2 3-benzyloxy-6-bromo-4-hydroxybenzaldehyde 

Downstream Products

• 105479-94-5 5-Benzyloxy-2-benzylsulfanyl-4-methoxy-benzaldehyde 
• 2973-59-3 2-bromoisovanillin 
• 612483-08-6 2-(5-benzyloxy-2-bromo-4-methoxyphenyl)-1,3-dioxane 
• 697803-43-3 (E)-3-benzyloxy-6-bromo-4-methoxy-β-chlorostyrene 
• 796843-30-6 4-benzyloxy-5,2',3',4'-tetramethoxy-biphenyl-2-carbaldehyde 
• 796843-31-7 4-benzyloxy-5,2',4'-trimethoxy-biphenyl-2-carbaldehyde 
• 918896-59-0 1-benzyloxy-4-bromo-2-methoxy-5-(2-nitro ethyl)benzene 
• 918896-60-3 2-[2-bromo-4-methoxy-5-benzyloxy]-1-(tert-butoxycarbonyl amino)-ethane 
• 1026439-42-8 (E)-3-[2-(2-Amino-ethyl)-4-benzyloxy-5-methoxy-phenyl]-acrylic acid ethyl ester 
• 1026556-60-4 (6-benzyloxy-7-methoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-acetic acid ethyl ester 
• 918896-63-6 6-benzyloxy-1-(2-hydroxy-ethyl)-7-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 918896-62-5 6-benzyloxy-1-ethoxycarbonylmethyl-7-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 918896-61-4 2-[2-(ethylpropionate)-4-methoxy-5-benzyloxy]-1-(tert-butoxycarbonyl-amino)-ethane 
• 918896-64-7 6-benzyloxy-1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-7-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

On the chloride lability in electron-rich second-generation ruthenium benzylidene complexes

A series of electron-rich second-generation cis-dichloro ruthenium aldehyde-chelating benzylidene complexes was prepared, characterized, and tested in typical ring-opening metathesis polymerization (ROMP) experiments. The benzylidene precursors were prepa

Preparation method of aporphine alkaloid

The invention discloses a preparation method of aporphine alkaloid as shown in a formula III. The method comprises the following steps: taking a benzaldehyde compound as shown in a formula III-0 as a raw material, and sequentially carrying out Wittig reaction, Pictet-Spengler reaction, Heck reaction and palladium carbon hydrogen deprotection. A bromine-containing benzaldehyde derivative is selected as a raw material, the carbon-carbon coupling co-production rate and the reaction rate are increased through bromine atoms, and the reaction activity is improved; benzyl chloroformate is adopted for NH protection, and an electron withdrawing group is introduced, so that the reaction yield can be improved; and a styrene methyl ether derivative directly reacts with an acylated phenylethylamine derivative in an acid catalysis system by adopting a one-pot method so as to obtain benzyl tetrahydroisoquinoline. The preparation method has the advantages of mild reaction conditions, low toxicity of used reagents, easily available raw materials, convenient post-treatment and simpler reaction route compared with previous reports, and can be suitable for various reaction substrates.

DIMERIC COMPOUNDS AS STING AGONISTS

The present disclosure relates to dimeric STING agonists of Formulae (I), (II), (III), (IV), (V), and (VI), and pharmaceutically acceptable salts thereof. The present disclosure also relates to methods of preparing the compounds and methods of using the c

Controlled Access to C1-Symmetrical Cyclotriveratrylenes (CTVs) by Using a Sequential Barluenga Boronic Coupling (BBC) Approach

We describe here a controlled approach to C1-symmetrical cyclotriveratrylenes (CTVs). In this approach dimers are synthesized through Barluenga boronic coupling (BBC) and after borylation, the last aromatic ring is introduced by a second BBC. After functional transformations of the trimers, the CTVs are formed using intramolecular SEAr. (Figure presented.).

Fused tricyclic compounds and application thereof in medicaments

The invention relates to fused tricyclic compounds and an application thereof in medicaments, and in particular to an application of the fused tricyclic compounds in medicaments for treating and/or preventing hepatitis B. In particular, the invention rela

FUSED TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE

The present invention relates to a fused tricyclic compound and application thereof in medicine, especially as a medicament for the treatment and/or prevention of hepatitis B. Specifically, the present invention relates to a compound having Formula (I) or

BIARYL AMIDES WITH MODIFIED SUGAR GROUPS FOR TREATMENT OF DISEASES ASSOCIATED WITH HEAT SHOCK PROTEIN PATHWAY

Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein. Formulae (I), (II), (III), (IV), and (V), Pharmaceutical compositions of the compounds are also provided. These biaryl amides and coumarin-based derivatives with modified sugar groups are useful for treatment and prevention of diseases and disorders, including neurological disorders, such as neurodegenerative diseases and nerve damaging disorders, for example, diabetic peripheral neuropathy.

Thermolytic Synthesis of Naphthalenes via Intramolecular Cyclocondensation of o -Phenylallylbenzaldehydes

The development of intramolecular carbonyl-ene type cyclocondensation of oxygenated o -phenylallylbenzaldehydes in refluxing decalin is reported. The facile and easy-to-operate thermolytic rearrangement procedure generates substituted naphthalenes in good to excellent yields.Georg Thieme Verlag Stuttgart - New York.

NOVEL 6,7-DIHYDROPYRIDO[2,1-A]PHTHALAZIN-2-ONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The invention provides novel compounds having the general formula: wherein R1 to R6 are as described herein, compositions including the compounds and methods of using the compounds.

COMPOSITIONS AND USES OF AMIDINE DERIVATIVES

Use of a compound of formula (I): wherein A, X, Y, R1 and R2 as defined herein, in treating hereditary angioedema is disclosed. A composition containing the compounds, a polar organic solvent or a mixture thereof; and optionally a co-solvent, is also disclosed.