(1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide

Base Information

Chemical Name:(1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide
CAS No.:350507-28-7
Molecular Formula:C₂₄H₃₂N₂O₂
Molecular Weight:380.53
Hs Code.:

Synonyms:(1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide

Suppliers and Price of (1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide

There total 3 articles about (1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 925-90-6
ethylmagnesium bromide

: 350507-27-6,288627-96-3
N-[(1R,2S)-2-(N,N-Diethylcarbamoyl)-2-phenylcyclopropylmethylene]benzylamine N-oxide

: 350507-28-7
(1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide

Guidance literature:: N-[(1R,2S)-2-(N,N-Diethylcarbamoyl)-2-phenylcyclopropylmethylene]benzylamine N-oxide; With magnesium bromide; In tetrahydrofuran; diethyl ether; at 20 ℃; for 0.5h;

ethylmagnesium bromide; In tetrahydrofuran; diethyl ether; at -78 ℃; for 8h; Further stages.;
DOI:10.1039/b008230i

Reference yield:

: 29601-98-7
N-benzylhydroxylamine hydrochloride

: 350507-28-7
(1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 93 percent / molecular sieves 4 Angstroem / CH₂Cl₂ / 1 h / 20 °C

2.1: MgBr₂ / diethyl ether; tetrahydrofuran / 0.5 h / 20 °C

2.2: 80 percent / diethyl ether; tetrahydrofuran / 8 h / -78 °C

With 4 A molecular sieve; magnesium bromide; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1039/b008230i

Reference yield:

: 172016-00-1
(1S,2R)-2-Formyl-1-phenyl-cyclopropanecarboxylic acid diethylamide

: 350507-28-7
(1S,2R)-1-Phenyl-2-[(S)-1-(N-benzyl-N-hydroxyamino)propyl]-N,N-diethylcyclopropanecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 93 percent / molecular sieves 4 Angstroem / CH₂Cl₂ / 1 h / 20 °C

2.1: MgBr₂ / diethyl ether; tetrahydrofuran / 0.5 h / 20 °C

2.2: 80 percent / diethyl ether; tetrahydrofuran / 8 h / -78 °C

With 4 A molecular sieve; magnesium bromide; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1039/b008230i