2-Phenylethylsuccinic acid

Base Information

Chemical Name:2-Phenylethylsuccinic acid
CAS No.:3448-42-8
Molecular Formula:C₁₂H₁₄O₄
Molecular Weight:222.241
Hs Code.:
UNII:6E1Z4CDA0N
Nikkaji Number:J1.739.059G

Synonyms:Phenylethylsuccinic acid;2-Phenylethylsuccinic acid;6E1Z4CDA0N;Butanedioic acid, (2-phenylethyl)-;UNII-6E1Z4CDA0N;Butanedioic acid, 2-(2-phenylethyl)-;3448-42-8;2-Phenethylsuccinic acid;Oprea1_688821;SCHEMBL10734883

Suppliers and Price of 2-Phenylethylsuccinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Phenylethylsuccinic acid

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:222.08920892
Heavy Atom Count:16
Complexity:243

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCC(CC(=O)O)C(=O)O

Technology Process of 2-Phenylethylsuccinic acid

There total 12 articles about 2-Phenylethylsuccinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 131156-36-0
dimethyl 2-(2-phenylethyl)succinate

: 3448-42-8
(+/-)-phenethylsuccinic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 5h; Heating;
DOI:10.1055/s-2002-23548

Reference yield:

: 6125-24-2
2-Phenylnitroethane

: 3448-42-8
(+/-)-phenethylsuccinic acid

Guidance literature:: Multi-step reaction with 3 steps

1: DBU / acetonitrile / 5 h / 20 °C

2: H₂ / 10 percent Pd/C / ethyl acetate / 6 h / 20 °C / 2068.59 Torr

3: 88 percent / aq. NaOH / ethanol / 5 h / Heating

With sodium hydroxide; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium on activated charcoal; In ethanol; ethyl acetate; acetonitrile; 1: Michael addition/elimination;
DOI:10.1055/s-2002-23548

Reference yield:

: 2-[2-Phenyl-eth-(E)-ylidene]-succinic acid dimethyl ester

: 3448-42-8
(+/-)-phenethylsuccinic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10 percent Pd/C / ethyl acetate / 6 h / 20 °C / 2068.59 Torr

2: 88 percent / aq. NaOH / ethanol / 5 h / Heating

With sodium hydroxide; hydrogen; palladium on activated charcoal; In ethanol; ethyl acetate;
DOI:10.1055/s-2002-23548