1,2 Bis(3-amino-4-hydroxyphenyl)ethane

Base Information

Chemical Name:1,2 Bis(3-amino-4-hydroxyphenyl)ethane
CAS No.:22428-33-7
Molecular Formula:C₁₄H₁₆N₂O₂
Molecular Weight:244.293
Hs Code.:
DSSTox Substance ID:DTXSID901280393
Nikkaji Number:J1.192.624J

Synonyms:SCHEMBL9008919;QFQNRDDXHNGFNW-UHFFFAOYSA-N;DTXSID901280393;1,2 bis(3-amino-4-hydroxyphenyl)ethane;22428-33-7;4,4a(2)-(1,2-Ethanediyl)bis[2-aminophenol]

Suppliers and Price of 1,2 Bis(3-amino-4-hydroxyphenyl)ethane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2 Bis(3-amino-4-hydroxyphenyl)ethane

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:244.121177757
Heavy Atom Count:18
Complexity:236

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1CCC2=CC(=C(C=C2)O)N)N)O

Technology Process of 1,2 Bis(3-amino-4-hydroxyphenyl)ethane

There total 5 articles about 1,2 Bis(3-amino-4-hydroxyphenyl)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 101133-41-9
bis(3-nitro-4-hydroxyphenyl)ethane

: 22428-33-7
bis(3-amino-4-hydroxyphenyl)ethane

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol; for 26h; under 2585.74 Torr;
DOI:10.1021/ja983778h

Reference yield:

: 120-44-5
1,4-di(4-methoxyphenyl)ethanone

: 22428-33-7
bis(3-amino-4-hydroxyphenyl)ethane

Guidance literature:: Multi-step reaction with 4 steps

1: 59 percent / Zn(Hg); 20 percent HCl / toluene / a) 40 deg C, 4 h, b) 100 deg C, overnight

2: 93 percent / BBr₃ / CH₂Cl₂ / 2 h / 20 °C

3: 57 percent / aq. HNO₃ / a) 25 deg C, 20 h, b) 2 d

4: 45 percent / H₂ / PtO₂ / ethanol / 26 h / 2585.74 Torr

With hydrogenchloride; hydrogen; nitric acid; boron tribromide; mercury; zinc; platinum(IV) oxide; In ethanol; dichloromethane; toluene; 1: Reduction / 2: demethylation / 3: Nitration / 4: Hydrogenation;
DOI:10.1021/ja983778h

Reference yield:

: 1657-55-2
1,2-bis(4-methoxyphenyl)ethane

: 22428-33-7
bis(3-amino-4-hydroxyphenyl)ethane

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / BBr₃ / CH₂Cl₂ / 2 h / 20 °C

2: 57 percent / aq. HNO₃ / a) 25 deg C, 20 h, b) 2 d

3: 45 percent / H₂ / PtO₂ / ethanol / 26 h / 2585.74 Torr

With hydrogen; nitric acid; boron tribromide; platinum(IV) oxide; In ethanol; dichloromethane; 1: demethylation / 2: Nitration / 3: Hydrogenation;
DOI:10.1021/ja983778h