2-Hydroxy-4-chlorphenylacetylen

Base Information

Chemical Name:2-Hydroxy-4-chlorphenylacetylen
CAS No.:36739-98-7
Molecular Formula:C₈H₅ClO
Molecular Weight:152.58
Hs Code.:

Synonyms:2-Hydroxy-4-chlorphenylacetylen

Suppliers and Price of 2-Hydroxy-4-chlorphenylacetylen

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Hydroxy-4-chlorphenylacetylen

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Hydroxy-4-chlorphenylacetylen

There total 3 articles about 2-Hydroxy-4-chlorphenylacetylen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 2420-26-0
4-chlorosalicylaldehyde

: 558-13-4
carbon tetrabromide

: 36739-98-7
2-Hydroxy-4-chlorphenylacetylen

Guidance literature:: 4-chlorosalicylaldehyde; carbon tetrabromide; With triphenylphosphine; In dichloromethane; at 0 ℃; for 2.33333h;

With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;
DOI:10.1021/acs.orglett.0c01096

Reference yield:

: C₁₁H₁₃ClOSi

: 36739-98-7
2-Hydroxy-4-chlorphenylacetylen

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;
DOI:10.1002/anie.202115554

Reference yield:

: 136808-72-5
2-iodo-5-chlorophenol

: 36739-98-7
2-Hydroxy-4-chlorphenylacetylen

Guidance literature:: Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / tetrahydrofuran / 18 h / 20 °C

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 - 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran;
DOI:10.1002/anie.202115554