methyl 3-O-benzyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate

Base Information

• Chemical Name: methyl 3-O-benzyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate
• CAS No.: 1227467-76-6
• Molecular Formula: C₂₆H₄₄O₈Si₂
• Molecular Weight: 540.802
• Mol file: 1227467-76-6.mol

Synonyms:methyl 3-O-benzyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate

Chemical Property of methyl 3-O-benzyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-O-benzyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate

There total 1 articles about methyl 3-O-benzyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane (69304-37-6) + methyl 3-O-benzyl-L-idopyranosyluronate (87326-77-0,87326-78-1) → methyl 3-O-benzyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate (1227467-76-6)

Guidance literature:

With 1H-imidazole; In acetonitrile; at -45 ℃; for 41h; Molecular sieve; Inert atmosphere;

DOI:10.1016/j.tet.2010.03.077

Reference yield: 68.0%

methyl 3-O-benzyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate (1227467-76-6) + levulinic acid (123-76-2) → methyl 3-O-benzyl-4-O-levulinyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate (1227467-77-7)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tet.2010.03.077

upstream raw materials:

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

methyl 3-O-benzyl-L-idopyranosyluronate

Downstream raw materials:

methyl 3-O-benzyl-4-O-levulinyl-1,2-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-α-L-idopyranuronate