3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose

Base Information

• Chemical Name: 3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose
• CAS No.: 123803-35-0
• Molecular Formula: C₂₁H₃₀O₄
• Molecular Weight: 346.467
• Mol file: 123803-35-0.mol

Synonyms:3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose

Chemical Property of 3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose

There total 2 articles about 3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-O-benzyl-5-cyclohexylidene-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose (123802-70-0) → 3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose (123803-35-0)

Guidance literature:

With hydrogen; nickel;

DOI:10.1016/0040-4039(90)80019-I

Reference yield:

3-O-benzyl-1,2-O-isopropylidene-α-D-ribo-pentodialdo-1,4-furanose (63593-02-2) → 3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose (123803-35-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) n-BuLi / 1) 1,2-dimethoxyethane

2: 100 percent / H₂ / Raney-Ni

With n-butyllithium; hydrogen; nickel;

DOI:10.1016/0040-4039(90)80019-I

Reference yield:

3-O-benzyl-5-cyclohexyl-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose (123803-35-0) → 2,3-di-O-benzyl-5-cyclohexyl-5-deoxy-D-ribofuranose

Guidance literature:

Multi-step reaction with 3 steps

1: HCl

2: NaH / dimethylformamide

3: HCl, AcOH, H₂O

With hydrogenchloride; water; sodium hydride; acetic acid; In N,N-dimethyl-formamide;

DOI:10.1016/0040-4039(90)80019-I

upstream raw materials:

3-O-benzyl-5-cyclohexylidene-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose

3-O-benzyl-1,2-O-isopropylidene-α-D-ribo-pentodialdo-1,4-furanose

Downstream raw materials:

(2R,3R,4R)-3,4-Bis-benzyloxy-2-cyclohexylmethyl-5-methoxy-tetrahydro-furan

(2S,3R,4R)-2,3-dibenzyloxy-5-cyclohexyl-1-morpholinopentan-4-ol

(2S,3R,4S)-4--L-norleucyl>amino-5-cyclohexyl-1-morpholino-2,3-pentadienol