benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid

Base Information

• Chemical Name: benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid
• CAS No.: 1263192-84-2
• Molecular Formula: C₁₈H₂₆N₂O₉
• Molecular Weight: 414.412
• Mol file: 1263192-84-2.mol

Synonyms:benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid

Chemical Property of benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid

There total 1 articles about benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H24N4O9 → benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid (1263192-84-2)

Guidance literature:

With trimethylphosphane; In tetrahydrofuran; methanol; water; at 20 ℃; for 16h; chemoselective reaction;

DOI:10.1016/j.bmcl.2009.08.044

Reference yield: 70.0%

benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid (1263192-84-2) + 4'-fluorobiphenyl-4-acetic acid N-hydroxysuccinimidyl ester (1296131-55-9) → benzyl 3,5,9-trideoxy-5-glycolamido-9-(4'-fluoro-4-biphenyl)acetamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid (1296131-48-0)

Guidance literature:

With sodium hydrogencarbonate; In water; acetonitrile; at 20 ℃; for 48h; pH=8 - 9;

DOI:10.1016/j.bmc.2011.01.060

Reference yield: 68.0%

benzyl 9-amino-3,5,9-trideoxy-5-glycolamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid (1263192-84-2) + 4’-hydroxy-[1,1‘-biphenyl]-4-carbaldehyde (100980-82-3) → benzyl 3,5,9-trideoxy-5-glycolamido-9-(4'-hydroxy-4-biphenyl)methylamino-D-glycero-α-D-galacto-2-nonulopyranosidonic acid (1296131-50-4)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In tetrahydrofuran; methanol; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2011.01.060

Downstream raw materials:

benzyl 3,5,9-trideoxy-5-glycolamido-9-(4'-fluoro-4-biphenyl)acetamido-D-glycero-α-D-galacto-2-nonulopyranosidonic acid

benzyl 3,5,9-trideoxy-5-glycolamido-9-(4'-hydroxy-4-biphenyl)methylamino-D-glycero-α-D-galacto-2-nonulopyranosidonic acid