2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt

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Chemical Name:2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt
CAS No.:1016651-01-6
Molecular Formula:C₂₁H₂₈F₂N₄O₆*ClH
Molecular Weight:506.934
Hs Code.:

2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt

Synonyms:2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt

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Chemical Property of 2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt

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Technology Process of 2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt

There total 2 articles about 2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1016651-09-4
(S)-N-{3-[3,5-difluoro-4-(4-(S)-2-tert-butoxycarbonylamino-methyl-4-methoxymethyl-piperidine-1-yl)phenyl]-2-oxo-oxazolidin-5-yl methyl}-acetamide

: 1016651-01-6
2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt

Guidance literature:: With hydrogenchloride; In isopropyl alcohol; at 20 ℃; Inert atmosphere;

Reference yield:

: 957796-51-9
(5S)-N-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

: 1016651-01-6
2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt

Guidance literature:: Multi-step reaction with 2 steps

1.1: dicyclohexyl-carbodiimide / dichloromethane / 0.5 h / 0 - 5 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: hydrogenchloride / isopropyl alcohol / 20 °C / Inert atmosphere

With hydrogenchloride; dicyclohexyl-carbodiimide; In dichloromethane; isopropyl alcohol;