5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile

Base Information

Chemical Name:5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile
CAS No.:1264924-62-0
Molecular Formula:C₁₈H₁₅N₅O
Molecular Weight:317.35
Hs Code.:

Synonyms:5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile

Suppliers and Price of 5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile

There total 3 articles about 5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1264926-40-0
C₁₂H₁₁ClN₂O

: 55338-73-3
5-amino-2-cyanopyridine

: 1264924-62-0
5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile

Guidance literature:: C₁₂H₁₁ClN₂O; 5-amino-2-cyanopyridine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 2h;

With ammonium chloride; In water; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 5720-05-8
4-methylphenylboronic acid

: 1264924-62-0
5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; 1,2-dimethoxyethane; water / 16 h / 100 °C / Inert atmosphere

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 20 °C

With sodium hydride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; toluene; mineral oil;

Reference yield:

: 5018-38-2
4,6-dichloro-5-methoxypyrimidine

: 1264924-62-0
5-[[5-methoxy-6-(4-methylphenyl)-4-pyrimidinyl]amino]-2-pyridinecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; 1,2-dimethoxyethane; water / 16 h / 100 °C / Inert atmosphere

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 20 °C

With sodium hydride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; toluene; mineral oil;