4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol

Base Information

Chemical Name:4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol
CAS No.:1132074-10-2
Molecular Formula:C₃₁H₄₂N₂O₂
Molecular Weight:474.687
Hs Code.:

Synonyms:4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol

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Technology Process of 4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol

There total 1 articles about 4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1132074-07-7
[2-(4-{2-[3-((1R)-3-diisopropylamino-1-phenyl-propyl)-4-hydroxy-phenyl]-ethoxy}-phenyl)-ethyl]-carbamic acid tert-butyl ester formate

: 1132074-10-2
4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol

Guidance literature:: [2-(4-{2-[3-((1R)-3-diisopropylamino-1-phenyl-propyl)-4-hydroxy-phenyl]-ethoxy}-phenyl)-ethyl]-carbamic acid tert-butyl ester formate; With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 3h;

With sodium hydroxide; water; In ethyl acetate;

Reference yield: 42.0%

: 1132074-10-2
4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol

: 100-52-7
benzaldehyde

: 1132074-47-5
4-{2-[4-(2-Benzylamino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol

Guidance literature:: 4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol; benzaldehyde; With acetic acid; In dichloromethane; at 20 ℃; for 0.5h;

With sodium tetrahydroborate; In dichloromethane; at 20 ℃;

With water; sodium hydrogencarbonate; In ethyl acetate;

Reference yield: 41.0%

: 1132074-10-2
4-{2-[4-(2-amino-ethyl)-phenoxy]-ethyl}-2-((1R)-3-diisopropylamino-1-phenyl-propyl)-phenol

: 3964-58-7
3-chloro-4-hydroxybenzoic acid

: 1132074-23-7
3-Chloro-N-[2-(4-{2-[3-((1R)-3-diisopropylamino-1-phenyl-propyl)-4-hydroxy-phenyl]-ethoxy}-phenyl)-ethyl]-4-hydroxy-benzamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;