((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene

Base Information

• Chemical Name: ((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene
• CAS No.: 1402748-84-8
• Molecular Formula: C₂₆H₂₃F₃O₂S
• Molecular Weight: 456.529
• Mol file: 1402748-84-8.mol

Synonyms:((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene

Chemical Property of ((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene

There total 5 articles about ((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(E)-(5,5,5-trifluoro-4-(phenylsulfonyl)pent-1-enyl)benzene (1402748-62-2) + ethyl (E)-3-phenyl-2-propenyl carbonate (106625-69-8) → ((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene (1402748-84-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 60 ℃; for 22h; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.09.094

Reference yield: 76.0%

β,β,β-trifluoroethyl phenyl sulfone (56354-44-0) + ethyl (E)-3-phenyl-2-propenyl carbonate (106625-69-8) → ((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene (1402748-84-8) + (E)-(5,5,5-trifluoro-4-(phenylsulfonyl)pent-1-enyl)benzene (1402748-62-2)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 60 ℃; for 22h; Time; Reagent/catalyst; Concentration; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.09.094

Reference yield:

thiophenol (108-98-5) → ((1E,6E)-4-(phenylsulfonyl)-4-(trifluoromethyl)hepta-1,6-diene-1,7-diyl)dibenzene (1402748-84-8)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / mineral oil; N,N-dimethyl-formamide

2: dihydrogen peroxide / acetic acid / 3 h / 100 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 22 h / 60 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; dihydrogen peroxide; sodium hydride; In tetrahydrofuran; acetic acid; N,N-dimethyl-formamide; mineral oil;

DOI:10.1016/j.tetlet.2012.09.094

upstream raw materials:

(E)-(5,5,5-trifluoro-4-(phenylsulfonyl)pent-1-enyl)benzene

ethyl (E)-3-phenyl-2-propenyl carbonate

β,β,β-trifluoroethyl phenyl sulfone

thiophenol