6-Methyldecan-1-amine

Base Information

• Chemical Name: 6-Methyldecan-1-amine
• CAS No.: 70010-83-2
• Molecular Formula: C₆H₉BrN₂O₆P₂
• Molecular Weight: 346.999
• European Community (EC) Number: 271-661-2
• DSSTox Substance ID: DTXSID30276079
• Mol file: 70010-83-2.mol

Synonyms:6-methyldecan-1-amine;68603-53-2;SCHEMBL3626123;DTXSID30276079;EINECS 271-661-2

Chemical Property of 6-Methyldecan-1-amine

Chemical Property:

• Vapor Pressure: 1.87E-21mmHg at 25°C
• Boiling Point: 715°Cat760mmHg
• Flash Point: 386.2°C
• Density: 2.21g/cm³
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 8
• Exact Mass: 171.198699802
• Heavy Atom Count: 12
• Complexity: 81.1

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: UVCB
• Canonical SMILES: CCCCC(C)CCCCCN

Technology Process of 6-Methyldecan-1-amine

There total 4 articles about 6-Methyldecan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

tetra(trimethylsilyl) (5-bromopyridin-2-ylamino)methylenebisphosphonate → [[(5-bromo-2-pyridinyl)amino]methylene]-1,1-bisphosphonate (70010-83-2)

Guidance literature:

With methanol; In diethyl ether; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.jorganchem.2020.121177

Reference yield:

[(5-bromo-pyridin-2-ylamino)-(diethoxy-phosphoryl)-methyl]-phosphonic acid diethyl ester → [[(5-bromo-2-pyridinyl)amino]methylene]-1,1-bisphosphonate (70010-83-2)

Guidance literature:

With hydrogenchloride; at 120 ℃;

DOI:10.1021/jm030084x

Reference yield:

N-(5-bromopyridin-2-yl)formamide (141354-32-7) → [[(5-bromo-2-pyridinyl)amino]methylene]-1,1-bisphosphonate (70010-83-2)

Guidance literature:

Multi-step reaction with 2 steps

1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 0.5 Torr / Inert atmosphere; Heating

2: methanol / diethyl ether / 20 °C / Inert atmosphere

With methanol; trimethylsilyl trifluoromethanesulfonate; In diethyl ether; dichloromethane;

DOI:10.1016/j.jorganchem.2020.121177

upstream raw materials:

N-(5-bromopyridin-2-yl)formamide

5-bromo-2-pyridylamine