C₅₅H₅₅N₅O₁₅

Base Information

• Chemical Name: C₅₅H₅₅N₅O₁₅
• CAS No.: 1450897-41-2
• Molecular Formula: C₅₅H₅₅N₅O₁₅
• Molecular Weight: 1026.07
• Mol file: 1450897-41-2.mol

Synonyms:C₅₅H₅₅N₅O₁₅

Chemical Property of C₅₅H₅₅N₅O₁₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₅H₅₅N₅O₁₅

There total 3 articles about C₅₅H₅₅N₅O₁₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5'-O-(4,4'-dimethoxytrityl)-3'-O-pivaloyloxymethyl-N6-phenoxyacetyl-adenosine (1146634-31-2) + 2,2'-[1,4-phenylenebis(oxy)]bisacetic acid (2245-53-6) → C55H55N5O15 (1450897-41-2)

Guidance literature:

With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; at 20 ℃; for 6h;

DOI:10.1016/j.bmc.2013.06.008

Reference yield:

5'-O-dimethoxytrityl-N6-phenoxyacetyladenosine (121076-16-2) → C55H55N5O15 (1450897-41-2)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrabutylammomium bromide; di(n-butyl)tin oxide / 1,2-dichloro-ethane / 1 h / 70 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; pyridine / 6 h / 20 °C

With pyridine; dmap; tetrabutylammomium bromide; di(n-butyl)tin oxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In 1,2-dichloro-ethane;

DOI:10.1016/j.bmc.2013.06.008

Reference yield:

iodomethyl pivaloate (53064-79-2) → C55H55N5O15 (1450897-41-2)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrabutylammomium bromide; di(n-butyl)tin oxide / 1,2-dichloro-ethane / 1 h / 70 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; pyridine / 6 h / 20 °C

With pyridine; dmap; tetrabutylammomium bromide; di(n-butyl)tin oxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In 1,2-dichloro-ethane;

DOI:10.1016/j.bmc.2013.06.008

upstream raw materials:

5'-O-(4,4'-dimethoxytrityl)-3'-O-pivaloyloxymethyl-N⁶-phenoxyacetyl-adenosine

2,2'-[1,4-phenylenebis(oxy)]bisacetic acid

5'-O-dimethoxytrityl-N₆-phenoxyacetyladenosine

iodomethyl pivaloate