2245-53-6Relevant academic research and scientific papers
Application of novel copper organic material for facile microextraction of sodium valproate from human plasma samples: Experimental design optimization and isotherm study
Bahrani, Sonia,Ghaedi, Mehrorang,Taghipour, Tahere,Mansoorkhani, Mohammad Javad Khoshnood,Bagheri, Ahmad Reza,Ostovan, Abbas
, (2018)
Well-designed metal organic materials (MOMs) were synthesized and applied for pre-concentration and determination of sodium valproate (Na-VP) from biological samples, bound to the copper complex of 1,4-phenylenedioxydiacetic acid under mild conditions. The channels of this sorbent provide high efficiency and also selectivity. The MOMs were structurally characterized using Fourier transform infrared and energy-dispersive X-ray spectroscopies, scanning electron microscopy and X-ray diffraction, and they were found to have suitable features for quantification of Na-VP using HPLC coupled with UV detection at λ?=?215?nm. Moreover, the rate of adsorption is improved by ultrasonic power and the experimental data are best fitted according to Freundlich adsorption isotherm. According to the central composite design, the best experimental conditions are 280.0?μl, 3.0?min and 17.0?mg for volume of eluent, sonication time and sorbent mass respectively. Calibration plots show linear responses towards Na-VP concentrations (0.4–18.0?μg ml?1), satisfactory limit of detection (0.06?μg ml?1, S/N?=?3) and reasonable enrichment factor (70.58). The coefficient of variation values of both inter- and intra-day analyses were less than 4.0%, indicating a candidate method for the determination of Na-VP in human plasma with reasonable recovery and efficiency.
Turning the heat on conjugated polyelectrolytes: An off-on ratiometric nanothermometer
Darwish, Ghinwa H.,Koubeissi, Ali,Shoker, Tharallah,Abou Shaheen, Samir,Karam, Pierre
, p. 823 - 826 (2016)
We report a self-referenced ratiometric nanothermometer based on short conjugated polyelectrolytes. An amphiphilic macromolecule destabilizes the polymer π-π stacking and makes it possible to shift the equilibrium between the less emissive aggregated state (520 nm) and the brighter individual chain (450 nm) within 20.0°C and 70.0°C.
Photoelectro-Fenton/photocatalytic process for decolorization of an organic compound by Ag:Cd-1,4-BDOAH2 nano-photocatalyst: Response surface modeling and central composite design optimization
Taghipour, Tahere,Karimipour, Gholamreza,Ghaedi, Mehrorang,Asfaram, Arash,Javadian, Hamedreza,Sabzehmeidani, Mohammad Mehdi,Karimi, Hajir
, (2021/04/19)
In the present research, the synthesis of the cadmium-benzene-1,4-dioxyacetic acid (Cd-1,4-BDOAH2) was carried out by the assistance of ultrasound waves, and then it was loaded with the low amount of Ag nano-particles. Subsequently, the Ag:Cd-1,4-BDOAH2 nano-photocatalyst was applied for photoelectro-Fenton/photocatalytic (PEF-PH) degradation of brilliant green (BG) in the existence of visible light in aqueous media. The synthesized composite was characterized by FTIR, SEM, EDX, TEM, XRD, DRS, and PL. The best operational conditions including time, initial BG concentration, pH, amount of photocatalyst, current and amount of FeCl3 on degradation efficiency (main and interactive) were as follows: 4 mg L?1 of BG at pH of 5, 0.4 g L?1 of Ag:Cd-1,4-BDOAH2, 250 mA of current, and 0.3 mmol L?1 of FeCl3 obtained by central composite design. The PEF-PH degradation kinetic data of BG were successfully fitted to Langmuir–Hinshelwood (L–H) model with the values of 1.16 mg L?1 min?1 and 0.018 L mg?1 for the rate constant (kr) and (KA), respectively.
A color-tunable fluorescent pillararene coordination polymer for efficient pollutant detection
Li, Xiang-Shuai,Li, Yong-Fu,Wu, Jia-Rui,Lou, Xin-Yue,Han, Junyou,Qin, Jianchun,Yang, Ying-Wei
supporting information, p. 3651 - 3657 (2020/02/26)
A dicarboxylatopillar[5]arene (DCP5)-based coordination polymer, namely DCP5-EuxTby, with color-tunable emission and capable of nitroaromatic pollutant detection, has been designed and fabricated via a typical metal-ligand coordination approach. Due to its rigid skeleton and electron-rich cavity, DCP5 plays an important role in this multi-color framework, not only as a linker but also as a blue-color fluorescence donor. Intriguingly, the fluorescent color of DCP5-EuxTby can be tuned from green to red simply by mediating the molar ratio of Eu3+ : Tb3+ in the functional system. More importantly, a white-color emitting system, that is, DCP5-Eu1Tb3, is discovered when the ratio of Eu3+ : Tb3+ is 1 : 3, and the white-light emissive DCP5-Eu1Tb3 exhibits good detection performance toward nitroaromatic pollutants in a wide application field. We envision that this work will open a new avenue for the exploration of synthetic macrocycle-based new materials in the construction of new fluorescent sensors and detectors for environmental sustainability and bio-related fields.
Microwave (MW), ultrasound (US) and combined synergic MW-US strategies for rapid functionalization of pharmaceutical use phenols
Pawe?czyk, Anna,Sowa-Kasprzak, Katarzyna,Olender, Dorota,Zaprutko, Lucjusz
, (2018/09/26)
Increasingly stringent regulations aimed at protection of the natural environment have stimulated the search for new synthetic methodologies in organic and medicinal chemistry having no or minimum harmful effect. An interesting approach is the use of alternative activation factors, microwaves (MW) or ultrasounds (US) and also their cross-combination, which has been tested in the fast and efficient creation of new structures. At present, an easy and green hybrid strategy (“Lego” chemistry) is generally recommended for the design of new substances from different chemistry building blocks. Often, selected biologically active components with specific chemical reactivities are integrated by a suitably designed homo- or heterodifunctional linker that modifies the functionality of the starting structure, allowing easy covalent linkage to another molecule. In this study, a fast introduction of heterodifunctional halogenoacidic linker to selected mono-, di- and triphenolic active substances, allowing their functionalization, was investigated. Nucleophilic substitution reaction was chosen to produce final ethers with the reactive carboxylic group from phenols. The functionalization was performed using various green factors initiating and supporting the chemical reactions (MW, US, MW-US). The benefits of the three green supporting methods and different conditions of reactions were analyzed and compared with the results of the reaction performed by conventional methods.
Organic precipitator as well as preparation method and application thereof
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Paragraph 0081-0083, (2018/09/08)
The invention belongs to the field of rare earth gathering, and particularly relates to an organic precipitator as well as a preparation method and application thereof. The organic precipitator provided by the invention is prepared from one or more of structural compounds of formula (I) to formula (III), wherein R1, R2, R3 and R'3 are independently selected from hydrogen, substituted or non-substituted linear chain alkyl with the number of carbon atoms of 1 to 10, substituted or non-substituted branched alkyl with the number of the carbon atoms of 3 to 10, and substituted or non-substituted aryl; n is a natural integer; and M indicates cations. The organic precipitator provided by the invention has good selectivity to the rare earth and is very suitable for gathering rare-earth elements in a low-concentration rare-earth solution. The experiment result shows that when the organic precipitator provided by the invention is used for gathering the rare earth in the low-concentration rare earth solution, the precipitation speed is high, the purity of the gathered rare earth product is greater than 96 percent, and the yield is greater than 95 percent. (The formula (I) to (III) are shown in the description).
Pillararene-Based Two-Component Thixotropic Supramolecular Organogels: Complementarity and Multivalency as Prominent Motifs
Zafrani, Yossi,Kaizerman, Dana,Hadar, Maya,Bigan, Nitzan,Granot, Eran,Ghosh, Moumita,Adler-Abramovich, Lihi,Patolsky, Fernando,Cohen, Yoram
supporting information, p. 15750 - 15755 (2018/08/06)
Rationally designed two-component supramolecular organogels based on multiple chemical interactions between percarboxylato- and peramino-pillararenes are described. Mixing low concentration solutions (gel values in some cases exceeding the boiling point of the embedded solvent. It is demonstrated that both structural complementarity and multivalency are important determinants in the gelation process of these attractive soft materials.
Reactions of peroxide products of ozonolysis of allyl ethers/esters in the AcOH-CH2Cl2 system on treatment with semicarbazide hydrochloride
Raskil'dina, Gulnara Z.,Legostaeva, Yuliya V.,Garifullina, Liliya R.,Sultanova, Rimma M.,Ishmuratov, Gumer Y.,Zlotskii, Simon S.
, p. 652 - 656 (2017/01/13)
Background: A one-pot method for the preparation of the corresponding alkoxy acetic acids by low-temperature ozonolysis of allyl ethers/esters followed by treatment with semicarbazide hydrochloride has been suggested. The reaction occurs via formation of acetoxyhydroperoxide, subsequent reduction of which depends on the process temperature and the nature of the starting substrate. Objective: The article is aimed at the development of one-pot method for obtaining practically important alkoxy acetic acids, because the ozonolytic cleavage of a ?=? double bond is the key step in full syntheses of many biologically active compounds. Methods: We used a low temperature ozonolysis of functionally substituted olefins in the system acetic acid-methylene dichloride followed by reduction of semicarbazide hydrochloride. To create a method we have used available allyl ethers/esters as starting materials. Results: We investigated reaction of the peroxide products of ozonolysis of monoallyl ethers, ester and diallyl ethers in an AcOH/CH2Cl2 mixture on treatment with semicarbazide hydrochloride at various temperatures. We have discovered that the selectivity of reduction of acetoxyhydroperoxide formed at the first stage depends both on the process temperature and on the nature of the starting substrate. A decrease in temperature favors acid hydrolysis and formation of a carboxylic acid. Conclusion: We have proposed a simple and highly efficient one-pot method for the preparation alkoxy acetic acids without isolation of intermediate peroxides.
Synthesis, Structure, and Properties of the 2-[5-(Aryloxyacetyl)-Amino-1,3,4-Thiadiazol-2-Ylthio] Propionate Derivatives
Hu, Bing,Zhai, Yue-Yuan,Zhang, Ling,Zhang, You-Ming,Wei, Tai-Bao
, p. 1337 - 1345 (2015/10/29)
A series of novel 2-[5-(aryloxyacetyl)-amino-1,3,4-thiadiazol-2-ylthio] propionate derivatives were synthesized in high yield, and their structures were characterized by IR, 1H NMR, 13C NMR, and elemental analysis, coupled with one selected single-crystal X-ray structure determination. The herbicidal activities of target compounds were assessed. The preliminary bioassay results showed that some compounds exhibited moderate to strong herbicidal symptoms in preemergence and postemergence tests. At 150 g/ha, S. tritici. show tolerance, while E. crus-galli L., E. Dahuricus, A. retroflexus, and C. glaucum L. were killed or severely injured. The activity of some compounds was comparable to the commercial herbicide 2,4-D. A suitable electron-withdrawing substituent at the 2-and/or 4-position of the phenyl ring was essential for high herbicidal activity. Moreover, the antifungal activities of the compounds have also been studied. The compounds were found to possess broad-spectrum antifungal activity.
Two 3D CdII and ZnII Complexes Based on Flexible Dicarboxylate Ligand and Nitrogen-containing Pillar: Synthesis, Structure, and Luminescent Properties
Liu, Liu,Fan, Yan-Hua,Wu, Lan-Zhi,Zhang, Huai-Min,Yang, Li-Rong
, p. 3749 - 3754 (2014/01/17)
Two 3D isomorphous and isostructural complexes, namely, [Zn(BDOA)(bpy)(H2O)2]n (1) and [Cd(BDOA)-(bpy)(H2O)2]n (2); (BDOA = Benzene-1,4-dioxyacetic acid, bpy = 4,4'-bipyridine) were synthesized under hydrothermal conditions and characterized by means of elemental analyses, thermogravimetric (TG), infrared spectrometry, and single crystal X-ray diffraction. Complexes 1 and 2 crystallize in the triclinic system, space group P-1 and each metal ion in the complexes are six-coordinated with the same coordination environment. In the as-synthesized complexes, BDOA2- anions link central metal ions to form a 1D zigzag chain [-BDOA2-Zn(Cd)-BDOA2-Zn(Cd)-]∞, whereas bpy pillars connect metal ions to generate a 1D linear chain [-bpy-Zn(Cd)-bpy-Zn(Cd)-] ∞. Both infinite chains are interweaved into 2D grid-like layers which are further constructed into a 3D open framework, where hydrogen bonds play as the bridges between the adjacent 2D layers. Luminescent properties of complex 1 showed selectivity for Hg2+ ion.
