ethyl 2,3-diamino-6-ethoxybenzoate

Base Information

• Chemical Name: ethyl 2,3-diamino-6-ethoxybenzoate
• CAS No.: 150368-39-1
• Molecular Formula: C₁₁H₁₆N₂O₃
• Molecular Weight: 224.26
• Mol file: 150368-39-1.mol

Synonyms:ethyl 2,3-diamino-6-ethoxybenzoate

Chemical Property of ethyl 2,3-diamino-6-ethoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2,3-diamino-6-ethoxybenzoate

There total 6 articles about ethyl 2,3-diamino-6-ethoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl 1-amino-6-ethoxy-3-nitrobenzoate (150368-38-0) → ethyl 2,3-diamino-6-ethoxybenzoate (150368-39-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 3h; under 2585.7 Torr;

DOI:10.1021/jm00068a010

Reference yield: 100.0%

→ ethyl 2,3-diamino-6-ethoxybenzoate (150368-39-1)

Guidance literature:

Reference yield:

2,6-Difluorobenzoic acid,ethyl ester (19064-14-3) → ethyl 2,3-diamino-6-ethoxybenzoate (150368-39-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 94 percent / nitric acid, conc. sulfuric acid / 0.5 h / Ambient temperature

2: 81 percent / 29percent aq. ammonium hydroxide / ethanol / 4 h

3: 84 percent / sodium hydroxide / 1 h / Ambient temperature

4: 100 percent / H₂ / 5percent Pd/C / ethyl acetate / 3 h / 2585.7 Torr

With ammonium hydroxide; sodium hydroxide; sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol; ethyl acetate;

DOI:10.1021/jm00068a010

upstream raw materials:

ethyl 1-amino-6-ethoxy-3-nitrobenzoate

2,6-Difluorobenzoic acid,ethyl ester

ethyl 2-amino-6-fluoro-3-nitrobenzoate

ethyl 2,6-difluoro-3-nitrobenzoate

Downstream raw materials:

2-Butyl-6-ethoxy-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]oxy]quinoxaline-5-carboxylic acid

2-methyl-1-(1-oxopropoxy)propyl-2-butyl-6-ethoxy-3-<<2'-1H-tetrazol-5-yl<1,1'-biphenyl>-4-yl>oxy>-5-quinoxalinecarboxylate