2-ammonio-2-phenylethyl sulfate

Base Information

• Chemical Name: 2-ammonio-2-phenylethyl sulfate
• CAS No.: 1437-78-1
• Molecular Formula: C₈H₁₁NO₄S
• Molecular Weight: 217.246
• Mol file: 1437-78-1.mol

Synonyms:2-ammonio-2-phenylethyl sulfate

Chemical Property of 2-ammonio-2-phenylethyl sulfate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ammonio-2-phenylethyl sulfate

There total 1 articles about 2-ammonio-2-phenylethyl sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

Phenylglycinol (20989-17-7,56613-80-0,71006-16-1,7568-92-5,188586-38-1) → 2-ammonio-2-phenylethyl sulfate (1437-78-1)

Guidance literature:

With chlorosulfonic acid; In acetonitrile; at 0 - 20 ℃; for 3.5h;

DOI:10.1021/jo302615g

Reference yield: 80.0%

2-ammonio-2-phenylethyl sulfate (1437-78-1) → 2-phenylaziridine (1499-00-9)

Guidance literature:

With sodium hydroxide; In water; toluene; for 18h; Reflux;

DOI:10.1021/jo302615g

Reference yield:

2-ammonio-2-phenylethyl sulfate (1437-78-1) → 2-Amino-1-phenylethanol (7568-93-6,1936-63-6)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / toluene; water / 18 h / Reflux

2: tetrahydrofuran / 0.5 h / 120 °C / Microwave irradiation; Sealed tube

3: hydrogenchloride; water / 10 h / 100 °C / Sealed tube

With hydrogenchloride; water; sodium hydroxide; In tetrahydrofuran; water; toluene;

DOI:10.1002/adsc.202100320

upstream raw materials:

Phenylglycinol

Downstream raw materials:

(rac)-4-phenyl-1,3-thiazolidine-2-thione

2-phenylaziridine

Phenylglycinol

2-Amino-1-phenylethanol