8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin

Base Information

Chemical Name:8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin
CAS No.:216580-53-9
Molecular Formula:C₂₃H₂₁NO₅
Molecular Weight:391.423
Hs Code.:

Synonyms:8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin

Suppliers and Price of 8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin

There total 2 articles about 8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.7%

: 65-85-0,8013-63-6
benzoic acid

: 216580-37-9
8-oxo-4,8-dihydro-2-phenyl-5-(3'-hydroxypropyl)-4H-pyridino[3,2-d]-m-dioxin

: 216580-53-9
8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm991080o

Reference yield:

: 216579-21-4
8-oxo-4,8-dihydro-2-phenyl-4H-pyrano[3,2-d]-m-dioxin

: 216580-53-9
8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin

Guidance literature:: Multi-step reaction with 2 steps

1: 77.8 percent / aq. NaOH / ethanol / 3 h / Heating; pH=12.5

2: 89.7 percent / Ph₃P; DEAD / tetrahydrofuran / 20 °C

With sodium hydroxide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; 1: Substitution / 2: Esterification;
DOI:10.1021/jm991080o

Reference yield: 85.0%

: 216580-53-9
8-oxo-4,8-dihydro-2-phenyl-5-[(3'-benzoyloxy)propyl]-4H-pyridino[3,2-d]-m-dioxin

: 1-[(3'-benzoyloxy)propyl]-2-hydroxymethyl-3-hydroxypyridin-4(1H)-one hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide; for 6h;
DOI:10.1021/jm991080o