Ethaverine

Base Information

Chemical Name:Ethaverine
CAS No.:486-47-5
Molecular Formula:C24H29 N O4
Molecular Weight:395.499
Hs Code.:
European Community (EC) Number:207-633-3
UNII:2H2HC19DYZ
DSSTox Substance ID:DTXSID3023009
Nikkaji Number:J6.010K
Wikidata:Q27166421
NCI Thesaurus Code:C73332
Metabolomics Workbench ID:143593
ChEMBL ID:CHEMBL1555736
Mol file:486-47-5.mol

Synonyms:Ethaquin;ethaverine;ethaverine hydrochloride;Ethquinol;ethylpapaverine

Suppliers and Price of Ethaverine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethaverine
10mg
$ 150.00

Total 13 raw suppliers

Chemical Property of Ethaverine

Chemical Property:

Vapor Pressure:1.13E-10mmHg at 25°C
Melting Point:99-101°
Refractive Index:1.6000 (estimate)
Boiling Point:527.1°Cat760mmHg
PKA:6.41±0.40(Predicted)
Flash Point:185.9°C
PSA：49.81000
Density:1.104g/cm³
LogP:5.42040
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:5.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:395.20965841
Heavy Atom Count:29
Complexity:462

Purity/Quality:

99% ^*data from raw suppliers

Ethaverine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(C=C(C=C1)CC2=NC=CC3=CC(=C(C=C32)OCC)OCC)OCC
Uses Ethaverine is an analogue of Papaverine (P190500), an antispasmodic. An isoquinoline derivative with the potential for antimicrobial, antimalarial and cytotoxic antiviral agents.
Therapeutic Function Spasmolytic, Vasodilator, Antiarrhythmic

Technology Process of Ethaverine

There total 8 articles about Ethaverine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 855692-23-8
6,7-diethoxy-1-(3,4-diethoxy-benzyl)-isoquinoline-3-carboxylic acid

: 486-47-5
ethaverine

Guidance literature:: With 1-Methylnaphthalene; at 240 ℃;
DOI:10.1016/S0040-4039(99)02045-6

Reference yield:

: 861-27-8
1-(3',4'-diethoxy-benzyl)-6,7-diethoxy-3,4-dihydro-isoquinoline

: 486-47-5
ethaverine

Guidance literature:: With palladium on activated charcoal; diisopropylbenzene;
DOI:10.1021/ja01166a009 DOI:10.1021/ja01173a530

Reference yield:

: 61381-04-2
2-(3,4-diethoxyphenyl)ethylamine

: 486-47-5
ethaverine

Guidance literature:: Multi-step reaction with 3 steps

1: 180 - 192 °C

2: phosphoryl chloride; benzene

3: palladium/charcoal; diisopropylbenzene

With palladium on activated charcoal; diisopropylbenzene; trichlorophosphate; benzene;
DOI:10.1021/ja01173a530