861-27-8

Upstream product

• 6298-46-0 N-(3,4-diethoxyphenylacetyl)-β-(3,4-diethoxyphenyl)ethylamine 
• 38464-04-9 3,4-diethoxy-phenyl-acetic acid 
• 61381-04-2 2-(3,4-diethoxyphenyl)ethylamine 

Downstream Products

• 182485-96-7 1-(3,4-Diethoxy-phenyl)-8,9-diethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinoline-2,3-dione 
• 1132818-03-1 2-[(6,7-diethoxy-3,4-dihydroisoquinolin-1-yl)(3,4-diethoxyphenyl)methylidene]-5,5-dimethyl-2,3,5,6-tetrahydropyrrolo[2,1-a]isoquinolin-3-one 
• 1401715-66-9 1-(3,4-diethoxyphenyl)-8,9-diethoxy-3-methyl-2-(trifluoromethyl)-5,6-dihydropyrrolo[2,1-a]isoquinoline 
• 54088-62-9 (6,7-diethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)(3,4-diethoxyphenyl)methanone 
• 1262209-64-2 14-(3,4-diethoxyphenyl)-11,12-diethoxy-2-methoxy-6-(trifluoromethyl)-8,9-dihydro-6H-chromeno[4',3':4,5]pyrrolo[2,1-a]isoquinoline 
• 1262209-65-3 2-bromo-14-(3,4-diethoxyphenyl)-11,12-diethoxy-6-(trifluoromethyl)-8,9-dihydro-6H-chromeno[4',3':4,5]pyrrolo[2,1-a]isoquinoline 
• 1262209-63-1 14-(3,4-diethoxyphenyl)-11,12-diethoxy-6-(trifluoromethyl)-8,9-dihydro-6H-chromeno[4',3':4,5]pyrrolo[2,1-a]isoquinoline 

Relevant academic research and scientific papers

Pharmaceutical compositions containing isoquinoline derivatives

Pharmaceutical compositions containing an isoquinoline derivative exhibit an excellent inhibitory action to an isozyme of phosphodiesterase of the type IV (PDEIV). The active component of the pharmaceutical composition is an isoquinoline derivative which is represented by the general formula: STR1 wherein R is an ethoxy group, or which is a pharmaceutically-acceptable salt of a compound represented by said formula. The isoquinoline derivatives have an excellent inhibitory action which is highly specific to PDEIV. They are highly useful as pharmaceuticals such as antidepressive agents, tranquilizers, antidemential agents, antiinflammatory agents, antiallergic agents, antiasthmatic agents, liver-protecting agents, and diuretic agents.