bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate

Base Information

• Chemical Name: bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate
• CAS No.: 1300734-61-5
• Molecular Formula: C₁₉H₂₇ClN₃O₆P
• Molecular Weight: 459.867
• Mol file: 1300734-61-5.mol

Synonyms:bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate

Chemical Property of bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate

There total 7 articles about bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-4-formyl-1,3-dimethylpyrazole (27006-76-4) → bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate (1300734-61-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium permanganate

2.1: thionyl chloride

3.1: ammonium hydroxide

3.2: 0 - 25 °C

With ammonium hydroxide; potassium permanganate; thionyl chloride;

DOI:10.1002/jhet.591

Reference yield:

C7H8O3S*C13H22NO5P (1202935-54-3) + 1,3-dimethyl-5-chloro-pyrazole-4-carbonyl chloride (27006-83-3) → bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate (1300734-61-5)

Guidance literature:

C₇H₈O₃S*C₁₃H₂₂NO₅P; With ammonium hydroxide;

1,3-dimethyl-5-chloro-pyrazole-4-carbonyl chloride; With triethylamine; In tetrahydrofuran; at 0 - 25 ℃;

DOI:10.1002/jhet.591

Reference yield:

C20H26NO5P → bis(2-methoxyethyl)((5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxamido)(phenyl)methyl)phosphonate (1300734-61-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: water

2.1: ammonium hydroxide

2.2: 0 - 25 °C

With ammonium hydroxide; In water;

DOI:10.1002/jhet.591

upstream raw materials:

C₇H₈O₃S*C₁₃H₂₂NO₅P

1,3-dimethyl-5-chloro-pyrazole-4-carbonyl chloride

benzaldehyde

1,3-dimethyl-5-pyrazolone

Refernces