C₂₁H₃₄N₂O

Base Information

• Chemical Name: C₂₁H₃₄N₂O
• CAS No.: 942347-52-6
• Molecular Formula: C₂₁H₃₄N₂O
• Molecular Weight: 330.514
• Mol file: 942347-52-6.mol

Synonyms:C₂₁H₃₄N₂O

Chemical Property of C₂₁H₃₄N₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₃₄N₂O

There total 7 articles about C₂₁H₃₄N₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C28H40N2O2 → C21H34N2O (942347-52-6)

Guidance literature:

With methanesulfonic acid; palladium 10% on activated carbon; hydrogen; In ethanol; water; at 65 ℃; for 8h; under 2250.23 Torr;

DOI:10.1021/op1002598

Reference yield:

3,3-dimethylpiperidine (1193-12-0) → C21H34N2O (942347-52-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrabutylammomium bromide; sodium hydroxide / water; 4-methyl-2-pentanone / 1 h / 80 °C

1.2: 50 - 80 °C

2.1: n-butyllithium / tetrahydrofuran; tert-butyl methyl ether / -20 °C

2.2: -20 - 0 °C

3.1: palladium 10% on activated carbon; methanesulfonic acid; hydrogen / ethanol; water / 8 h / 65 °C / 2250.23 Torr

With n-butyllithium; methanesulfonic acid; palladium 10% on activated carbon; tetrabutylammomium bromide; hydrogen; sodium hydroxide; In tetrahydrofuran; ethanol; tert-butyl methyl ether; water; 4-methyl-2-pentanone;

DOI:10.1021/op1002598

Reference yield:

1-{3-[(4-bromophenyl)oxy]propyl}-3,3-dimethylpiperidine (1256920-58-7) → C21H34N2O (942347-52-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; tert-butyl methyl ether / -20 °C

1.2: -20 - 0 °C

2.1: palladium 10% on activated carbon; methanesulfonic acid; hydrogen / ethanol; water / 8 h / 65 °C / 2250.23 Torr

With n-butyllithium; methanesulfonic acid; palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; ethanol; tert-butyl methyl ether; water;

DOI:10.1021/op1002598

upstream raw materials:

3,3-dimethylpiperidine

1-{3-[(4-bromophenyl)oxy]propyl}-3,3-dimethylpiperidine

4,4-dimethyl-5-oxopentanenitrile

2,2-dimethylglutaric acid

Downstream raw materials:

C₄₂H₄₈N₂O₄

phenylmethyl (2E)-3-(4-{[4-(4-{[3-(3,3-dimethyl-1-piperidinyl)propyl]oxy}phenyl)-1-piperidinyl]-carbonyl}-1-naphthalenyl)-2-propenoate fumarate