6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline

Base Information

Chemical Name:6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline
CAS No.:1600563-34-5
Molecular Formula:C₁₈H₁₂BrClF₃NO₂
Molecular Weight:446.651
Hs Code.:

Synonyms:6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline

Suppliers and Price of 6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline

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Chemical Property of 6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline

Chemical Property:

Purity/Quality:

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Technology Process of 6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline

There total 4 articles about 6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1600563-33-4
6-bromo-2,4-dichloro-8-methyl-3-(4-(trifluoromethoxy)phenyl)quinoline

: 124-41-4
sodium methylate

: 1600563-34-5
6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline

Guidance literature:: In methanol; toluene; at 110 ℃; for 24h; Sealed tube;

Reference yield:

: 103962-05-6
1-iodo-4-(trifluoromethoxy)benzene

: 1600563-34-5
6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline

Guidance literature:: Multi-step reaction with 4 steps

1: 2-Picolinic acid; caesium carbonate; copper(l) iodide / 1,4-dioxane / 48 h / 20 °C / Inert atmosphere

2: sodium hydroxide / water / 1 h / 100 °C

3: trichlorophosphate / 3 h / 105 °C

4: methanol; toluene / 24 h / 110 °C / Sealed tube

With 2-Picolinic acid; copper(l) iodide; caesium carbonate; sodium hydroxide; trichlorophosphate; In 1,4-dioxane; methanol; water; toluene;

Reference yield:

: 773139-64-3
diethyl 2-(4-(trifluoromethoxy)phenyl)malonate

: 1600563-34-5
6-brorno-4-chloro-2-rnethoxy-8-methyl-3-(4-(t:rifluoromethoxy)phenyl)quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / water / 1 h / 100 °C

2: trichlorophosphate / 3 h / 105 °C

3: methanol; toluene / 24 h / 110 °C / Sealed tube

With sodium hydroxide; trichlorophosphate; In methanol; water; toluene;