Pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, monosodiumsalt, (6a,11b)-

Base Information

• Chemical Name: Pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, monosodiumsalt, (6a,11b)-
• CAS No.: 2375-03-3
• Molecular Formula: C26H33NaO8
• Molecular Weight: 497.59
• European Community (EC) Number: 219-156-8
• Wikipedia: Methylprednisolone_succinate
• Mol file: 2375-03-3.mol

Synonyms:2375-03-3;Pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, monosodiumsalt, (6a,11b)-;s6593;6 alpha -Methylprednisolone 21-hemisuccinate sodium salt;6alpha-Methylprednisolone 21-hemisuccinate sodium salt, lyophilized powder;(6alpha,11beta)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-pregna-1,4-diene-3,20-dione, Monosodium Salt;11beta,17,21-trihydroxy-6alpha-methyl-, 21-(hydrogen succinate)pregna-1,4-diene-3,20-dione Monosodium Salt

Chemical Property of Pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, monosodiumsalt, (6a,11b)-

Chemical Property:

• Appearance/Colour: lyophilized powder
• Boiling Point: 689.6 °C at 760 mmHg
• Flash Point: 230.7 °C
• PSA: 141.03000
• LogP: 0.88460
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 7
• Exact Mass: 497.21513732
• Heavy Atom Count: 35
• Complexity: 981

Purity/Quality:

98%,99%, ^*data from raw suppliers

Succinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 61-40
• Safety Statements: 53-22-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)O)O.[Na]
• Isomeric SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)O)O.[Na]
• Recent EU Clinical Trials: EARLY TREATMENT OF PNEUMONIA COVID-19 WITH GLUCOCORTICOIDS.
• Uses: 6α-Methylprednisolone 21-Hemisuccinate is a glucocorticosteroid used in anti-inflammatory medication in the treatment of spinal cord injuries. 6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.