N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

Base Information

• Chemical Name: N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide
• CAS No.: 1255188-34-1
• Molecular Formula: C₂₆H₂₉NO₅
• Molecular Weight: 435.52
• Mol file: 1255188-34-1.mol

Synonyms:N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

Chemical Property of N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

There total 1 articles about N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

3-(2,6-dimethoxyphenyl)propanoic acid (6683-69-8) + 2-(2-(benzyloxy)phenoxy)ethanamine (72955-81-8) → N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide (1255188-34-1)

Guidance literature:

3-(2,6-dimethoxyphenyl)propanoic acid; With chloroformic acid ethyl ester; triethylamine; In chloroform; at 0 ℃; for 0.5h;

2-(2-(benzyloxy)phenoxy)ethanamine; In chloroform; at 20 ℃; for 3h;

DOI:10.1016/j.bmc.2010.08.002

Reference yield: 63.0%

N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide (1255188-34-1) → N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxyphenyl)propan-1-amine (1255187-83-7)

Guidance literature:

N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide; With dimethylsulfide borane complex; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 60 ℃; for 1h;

With sodium hydroxide; In water;

DOI:10.1016/j.bmc.2010.08.002

upstream raw materials:

3-(2,6-dimethoxyphenyl)propanoic acid

2-(2-(benzyloxy)phenoxy)ethanamine

Downstream raw materials:

N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxyphenyl)propan-1-amine