N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

Base Information

Chemical Name:N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide
CAS No.:1255188-34-1
Molecular Formula:C₂₆H₂₉NO₅
Molecular Weight:435.52
Hs Code.:

Synonyms:N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

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Chemical Property of N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

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Technology Process of N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

There total 1 articles about N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 6683-69-8
3-(2,6-dimethoxyphenyl)propanoic acid

: 72955-81-8
2-(2-(benzyloxy)phenoxy)ethanamine

: 1255188-34-1
N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

Guidance literature:: 3-(2,6-dimethoxyphenyl)propanoic acid; With chloroformic acid ethyl ester; triethylamine; In chloroform; at 0 ℃; for 0.5h;

2-(2-(benzyloxy)phenoxy)ethanamine; In chloroform; at 20 ℃; for 3h;
DOI:10.1016/j.bmc.2010.08.002

Reference yield: 63.0%

: 1255188-34-1
N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide

: 1255187-83-7
N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxyphenyl)propan-1-amine

Guidance literature:: N-(2-(2-(benzyloxy)phenoxy)ethyl)-3-(2,6-dimethoxy phenyl)propanamide; With dimethylsulfide borane complex; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 60 ℃; for 1h;

With sodium hydroxide; In water;
DOI:10.1016/j.bmc.2010.08.002