tert-butyldimethylsilyl 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-α-D-glucopyranoside

Base Information

• Chemical Name: tert-butyldimethylsilyl 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-α-D-glucopyranoside
• CAS No.: 1085377-66-7
• Molecular Formula: C₄₀H₄₆Cl₃N₃O₁₁Si
• Molecular Weight: 879.263
• Mol file: 1085377-66-7.mol

Synonyms:tert-butyldimethylsilyl 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-α-D-glucopyranoside

Chemical Property of tert-butyldimethylsilyl 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyldimethylsilyl 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-α-D-glucopyranoside

There total 1 articles about tert-butyldimethylsilyl 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-(o-nitrophthalimido)butyric acid (10264-75-2) + C28H38Cl3NO6Si (1085377-63-4) → tert-butyldimethylsilyl 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-α-D-glucopyranoside (1085377-66-7)

Guidance literature:

With pyridine; dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol802229b

Reference yield: 93.0%

tert-butyldimethylsilyl 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-α-D-glucopyranoside (1085377-66-7) → 3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-β-D-glucopyranoside (1085377-68-9)

Guidance literature:

With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1021/ol802229b

upstream raw materials:

4-(o-nitrophthalimido)butyric acid

C₂₈H₃₈Cl₃NO₆Si

Downstream raw materials:

3,4-di-O-benzyl-6-(4'-(o-nitrophthalimido)butyryl)-2-deoxy-2-trichloroacetylamino-β-D-glucopyranoside