(S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene

Base Information

• Chemical Name: (S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene
• CAS No.: 612503-69-2
• Molecular Formula: C₂₅H₂₈N₄S
• Molecular Weight: 416.59
• Mol file: 612503-69-2.mol

Synonyms:(S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene

Chemical Property of (S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of (S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene

There total 1 articles about (S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-(3-phenyl-propyl)-piperazine (612503-64-7) + 2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine (612503-08-9) → (S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene (612503-69-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; toluene; at 110 ℃; for 24h;

Reference yield: 86.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + (S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene (612503-69-2) → (S)-2-methyl-10-(3-(3-phenyl-propyl)-4-methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene

Guidance literature:

formaldehyd; (S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene; With water; sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 4h;

With sodium hydrogencarbonate; In water; 1,2-dichloro-ethane;

Reference yield:

(S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene (612503-69-2) → (S)-2-methyl-10-(3-(3-phenyl-propyl)-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene dihydrochloride

Guidance literature:

With ammonium chloride; In methanol;

upstream raw materials:

(S)-2-(3-phenyl-propyl)-piperazine

2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine