(R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol

Base Information

• Chemical Name: (R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol
• CAS No.: 291533-31-8
• Molecular Formula: C₃₂H₃₃NO₅
• Molecular Weight: 511.618
• Mol file: 291533-31-8.mol

Synonyms:(R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol

Chemical Property of (R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol

There total 1 articles about (R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-4'-benzyloxyacetophenone (151323-99-8) → (R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol (291533-31-8)

Guidance literature:

With trans-RuCl₂[(R)-xylbinap][(R)-daipen]; potassium tert-butylate; In isopropyl alcohol; tert-butyl alcohol; at 25 ℃; for 24h; under 6080.41 Torr;

DOI:10.1021/ja001098k

Reference yield:

(R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol (291533-31-8) → (R)-1-(4-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol Monohydrochloride

Guidance literature:

With hydrogenchloride; potassium hydroxide; In ethanol; water;

Reference yield:

(R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol (291533-31-8) → (R)-1-(p-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol (63365-60-6)

Guidance literature:

With potassium hydroxide; In methanol; for 10h; Heating;

DOI:10.1021/ja001098k

upstream raw materials:

2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-4'-benzyloxyacetophenone

Downstream raw materials:

(R)-1-(p-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol