63365-60-6

Basic information

• Product Name: (R)-1-(p-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol
• Synonyms: (R)-1-(p-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol
• CAS NO: 63365-60-6
• Molecular Weight: 407.51
• Mol File: 63365-60-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-1-(p-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(p-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol(63365-60-6)
• EPA Substance Registry System: (R)-1-(p-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol(63365-60-6)

Safety Data

• Hazardous Substances Data: 63365-60-6(Hazardous Substances Data)

Upstream product

• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 102282-10-0 (R)-2-(4-benzyloxyphenyl)oxirane 
• 10313-60-7 3,4-dimethoxyphenylacetyl chloride 
• 831196-82-8 N-[2-(4-benzyloxy-phenyl)-2-hydroxy-ethyl]-2-(3,4-dimethoxy-phenyl)-acetamide 
• 831196-83-9 p-benzyloxy-ω-azidoacetophenone 
• 131965-54-3 (R)-(+)-2-bromo-1-(4'-benzyloxyphenyl) ethanol 
• 473552-31-7 (R)-1-(4-benzyloxyphenyl)-2-(p-tolylsulfonyloxy)ethanol 
• 4254-67-5 2-bromo-1-(4-benzyloxyphenyl)-1-ethanone 
• 473552-22-6 (R)-(-)-2-azido-1-(4-benzyloxyphenyl)-1-ethanol 
• 473552-26-0 (R)-(-)-2-amino-1-(p-benzyloxyphenyl)ethanol 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 291533-31-8 (R)-2-[(benzoyl){2-(3,4-dimethoxyphenyl)ethyl}amino]-1-(4-benzyloxyphenyl)ethanol 

Downstream Products

• 71771-90-9 denopamine 

Relevant articles and documents

Asymmetric transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanone derivatives: synthesis of (R)-tembamide, (R)-aegeline, (R)-octopamine, and (R)-denopamine

Catalytic transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanone derivatives leads to efficient synthesis of β-adrenergic agonists, (R)-tembamide, (R)-aegeline, (R)-octopamine, and (R)-denopamine.

A convenient stereoselective synthesis of (R)-(-)-denopamine and (R)-(-)-salmeterol

β-Adrenoreceptor agonists (R)-(-)-denopamine (R)-1 and (R)-(-)-salmeterol (R)-2 have been prepared in good overall yield and high enantioselectivity through a biotransformative pathway.